TYRPHOSTIN AG 1024
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- $35 - $5128
- Product name: TYRPHOSTIN AG 1024
- CAS: 65678-07-1
- MF: C14H13BrN2O
- MW: 305.17
- EINECS:
- MDL Number:MFCD02179365
- Synonyms:2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile;AGS 200;Tyrphostin;2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile AGS 200;AG-1024;HY-10253; AG 1024; AGS 200;HY-10253;AG-1024 (Tyrphostin);2-(3-broMo-5-tert-butyl-4-hydroxybenzylidene)Malononitrile
36 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1000mg
- 1g
- ManufacturerAK Scientific
- Product numberY0366
- Product description2-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
- Packaging1mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0366
- Product description2-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
- Packaging5mg
- Price$127
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging5mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging10mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging25mg
- Price$267
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging50mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging100mg
- Price$584
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA114134
- Product descriptionAG 1024 98+%
- Packaging1g
- Price$5128
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000021
- Product descriptionAG 1024 95.00%
- Packaging1MG
- Price$445
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000021
- Product descriptionAG 1024 95.00%
- Packaging5MG
- Price$465
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2673
- Product descriptionAG 1024
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2673
- Product descriptionAG 1024
- Packaging10mM(in 1mL DMSO)
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2673
- Product descriptionAG 1024
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2673
- Product descriptionAG 1024
- Packaging25mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60363
- Product descriptionAG 1024 ≥98%
- Packaging10mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180915
- Product descriptionAG-1024 (Tyrphostin) >98%
- Packaging100mg
- Price$542.3
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0366 | 2-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile | 1mg | $100 | 2021-12-16 | Buy |
| AK Scientific | Y0366 | 2-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile | 5mg | $127 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 5mg | $106 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 10mg | $158 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 25mg | $267 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 50mg | $400 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 100mg | $584 | 2021-12-16 | Buy |
| Ambeed | A114134 | AG 1024 98+% | 1g | $5128 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000021 | AG 1024 95.00% | 1MG | $445 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000021 | AG 1024 95.00% | 5MG | $465 | 2021-12-16 | Buy |
| ApexBio Technology | A2673 | AG 1024 | 5mg | $65 | 2021-12-16 | Buy |
| ApexBio Technology | A2673 | AG 1024 | 10mM(in 1mL DMSO) | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A2673 | AG 1024 | 10mg | $110 | 2021-12-16 | Buy |
| ApexBio Technology | A2673 | AG 1024 | 25mg | $225 | 2021-12-16 | Buy |
| Arctom | CFN60363 | AG 1024 ≥98% | 10mg | $258 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180915 | AG-1024 (Tyrphostin) >98% | 100mg | $542.3 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble
form :solid
color :yellow
solubility :DMSO: soluble
form :solid
color :yellow
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) initiates a cascade of reactions that promote cell growth and transformation by activating the PI3K/Akt signaling pathway, inhibiting apoptotic pathways, and mediating mitogenic actions. Overexpression of IGF-1R confers tumorigenic potential to cells as well as protection from apoptosis. AG-1024 is a selective inhibitor of IGF-1R that inhibits insulin-stimulated cellular proliferation and IGF-1R autophosphorylation with IC50 values of 0.4 and 7 μM, respectively. At 10 nM, AG-1024 can inhibit proliferation and induce apoptosis in human breast cancer MCF-7 cells, and it inhibits autocrine growth of human prostate cancer DU145 cells with an IC50 value of 2.5 μM.More related product prices
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