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ChemicalBook >> CAS DataBase List >> Sulfadiazine

Sulfadiazine

Sulfadiazine price.
  • $5 - $957.1
  • Product name: Sulfadiazine
  • CAS: 68-35-9
  • MF: C10H10N4O2S
  • MW: 250.28
  • EINECS:200-685-8
  • MDL Number:MFCD00006065
  • Synonyms:4-amino-N-2-pyrimidinyl;4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide;Sulfadiazine zinc salt;Eksadiazine;4-azanyl-N-pyrimidin-2-yl-benzenesulfonamide;Sulfadiazine Base & Sodium;Sulfadiazine,4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide;Sulfadiazine (200 mg)
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  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Atlantic Research Chemicals
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • y0001480
  • 100μg
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  • 500mg
  • 5g
  • 50μg
  • 100mg
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  • 200mg
  • s1800000
  • 10mM(in 1mL DMSO)
  • 10g
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  • 500g
  • 1kg
  • 1000g
  • 50gm:
  • ManufacturerAK Scientific
  • Product numberJ92774
  • Product descriptionSulfadiazine
  • Packaging25g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10656
  • Product descriptionSulfadiazine
  • Packaging100mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10656
  • Product descriptionSulfadiazine
  • Packaging1g
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12370
  • Product descriptionSulfadiazine, 99%
  • Packaging50g
  • Price$28.4
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12370
  • Product descriptionSulfadiazine, 99%
  • Packaging250g
  • Price$88.1
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA12370
  • Product descriptionSulfadiazine, 99%
  • Packaging1000g
  • Price$243.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA293414
  • Product description4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA293414
  • Product description4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98%
  • Packaging25g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA293414
  • Product description4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98%
  • Packaging100g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA293414
  • Product description4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98%
  • Packaging500g
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA293414
  • Product description4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98%
  • Packaging1kg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8527
  • Product descriptionSulfadiazine
  • Packaging5g
  • Price$76
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8527
  • Product descriptionSulfadiazine
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021143
  • Product descriptionSulfadiazine 98%
  • Packaging25g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021143
  • Product descriptionSulfadiazine 98%
  • Packaging100g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021143
  • Product descriptionSulfadiazine 98%
  • Packaging500g
  • Price$67
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J92774 Sulfadiazine 25g $15 2021-12-16 Buy
AK Scientific J10656 Sulfadiazine 100mg $39 2021-12-16 Buy
AK Scientific J10656 Sulfadiazine 1g $94 2021-12-16 Buy
Alfa Aesar A12370 Sulfadiazine, 99% 50g $28.4 2024-03-01 Buy
Alfa Aesar A12370 Sulfadiazine, 99% 250g $88.1 2024-03-01 Buy
Alfa Aesar A12370 Sulfadiazine, 99% 1000g $243.65 2024-03-01 Buy
Ambeed A293414 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98% 100mg $5 2021-12-16 Buy
Ambeed A293414 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98% 25g $8 2021-12-16 Buy
Ambeed A293414 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98% 100g $15 2021-12-16 Buy
Ambeed A293414 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98% 500g $68 2021-12-16 Buy
Ambeed A293414 4-Amino-N-(pyrimidin-2-yl)benzenesulfonamide 98% 1kg $100 2021-12-16 Buy
ApexBio Technology A8527 Sulfadiazine 5g $76 2021-12-16 Buy
ApexBio Technology A8527 Sulfadiazine 10mM(in 1mL DMSO) $80 2021-12-16 Buy
Arctom AS021143 Sulfadiazine 98% 25g $8 2021-12-16 Buy
Arctom AS021143 Sulfadiazine 98% 100g $15 2021-12-16 Buy
Arctom AS021143 Sulfadiazine 98% 500g $67 2021-12-16 Buy

Properties

Melting point :253 °C (dec.) (lit.)
Boiling point :512.6±52.0 °C(Predicted)
Density :1.3780 (rough estimate)
refractive index :1.6440 (estimate)
storage temp. :2-8°C
solubility :Soluble in dimethyl sulfoxide.
pka :pKa 2.21(H2O t = 25 I = 0.5 (NaCl)) (Uncertain)
form :powder
color :white
Water Solubility :67.13mg/L(25 ºC)
Merck :14,8903
BRN :6733588
BCS Class :4/3
CAS DataBase Reference :68-35-9(CAS DataBase Reference)
NIST Chemistry Reference :Sulfadiazine(68-35-9)
EPA Substance Registry System :Benzenesulfonamide, 4-amino-N-2-pyrimidinyl- (68-35-9)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Sulfadiazine is an oral sulfonamide anti-bacterial agent. it is a synthetic pyrimidinyl sulfonamide derivative, The chemical classification of sulfadiazine is Sulfonamides.The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Sulfadiazine is used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

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