Stattic
- $35 - $2200
- Product name: Stattic
- CAS: 19983-44-9
- MF: C8H5NO4S
- MW: 211.19
- EINECS:
- MDL Number:MFCD00173799
- Synonyms:BUTTPARK 97\04-73;6-NITRO-1H-1LAMBDA6-BENZO[B]THIOPHENE-1,1-DIONE;AKOS 1001;6-Nitro-1-benzothiophene 1,1-dioxide;1,1-DIOXO-6-NITROBENZO(B)THIOPHENE;6-Nitrobenzo[b]thiophene-1,1-dioxide, Stat three inhibitory compound;Stattic;6-Nitrobenzo[b]thiophene1,1-dioxide
57 prices
Selected condition:
Brand
- Acints
- Advanced Chemicals Intermediatesced Chemicals Intermediates
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- Tocris
- TRC
- Usbiological
Package
- 10mg
- 25mg
- 20mg
- 10
- 50mg
- 250mg
- 500mg
- 100mg
- 50
- 1000mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAcints
- Product numberACI-03835
- Product description6-Nitro-benzo[b]thiophene1,1-dioxide 95%+
- Packaging1g
- Price$143.55
- Updated2021-12-16
- Buy
- ManufacturerAcints
- Product numberACI-03835
- Product description6-Nitro-benzo[b]thiophene1,1-dioxide 95%+
- Packaging5g
- Price$651.05
- Updated2021-12-16
- Buy
- ManufacturerAdvanced Chemicals Intermediatesced Chemicals Intermediates
- Product numberACI-03835
- Product description6-Nitro-benzo[b]thiophene1,1-dioxide 95%+
- Packaging1g
- Price$143.55
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2729AH
- Product descriptionStattic
- Packaging1g
- Price$541
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging10mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging25mg
- Price$52
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging50mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging100mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging250mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA109795
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging1g
- Price$446
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2224
- Product descriptionStattic
- Packaging100mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2224
- Product descriptionStattic
- Packaging10mM(in 1mL DMSO)
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2224
- Product descriptionStattic
- Packaging25mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS434424
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging10mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS434424
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging25mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS434424
- Product description6-Nitrobenzo[b]thiophene1,1-dioxide 98%
- Packaging50mg
- Price$78
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Acints | ACI-03835 | 6-Nitro-benzo[b]thiophene1,1-dioxide 95%+ | 1g | $143.55 | 2021-12-16 | Buy |
Acints | ACI-03835 | 6-Nitro-benzo[b]thiophene1,1-dioxide 95%+ | 5g | $651.05 | 2021-12-16 | Buy |
Advanced Chemicals Intermediatesced Chemicals Intermediates | ACI-03835 | 6-Nitro-benzo[b]thiophene1,1-dioxide 95%+ | 1g | $143.55 | 2021-12-16 | Buy |
AK Scientific | 2729AH | Stattic | 1g | $541 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 10mg | $35 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 25mg | $52 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 50mg | $79 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 100mg | $118 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 250mg | $178 | 2021-12-16 | Buy |
Ambeed | A109795 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 1g | $446 | 2021-12-16 | Buy |
ApexBio Technology | A2224 | Stattic | 100mg | $200 | 2021-12-16 | Buy |
ApexBio Technology | A2224 | Stattic | 10mM(in 1mL DMSO) | $55 | 2021-12-16 | Buy |
ApexBio Technology | A2224 | Stattic | 25mg | $80 | 2021-12-16 | Buy |
Arctom | AS434424 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 10mg | $35 | 2021-12-16 | Buy |
Arctom | AS434424 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 25mg | $51 | 2021-12-16 | Buy |
Arctom | AS434424 | 6-Nitrobenzo[b]thiophene1,1-dioxide 98% | 50mg | $78 | 2021-12-16 | Buy |
Properties
Melting point :187-188 °C
Boiling point :461.1±45.0 °C(Predicted)
Density :1.621±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :461.1±45.0 °C(Predicted)
Density :1.621±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: >20mg/mL
form :powder
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
Signal transducers and activators of transcription (STATs) are a family of latent cytoplasmic transcription factors that convey signals from the cell membrane to the nucleus. In various human tumors, STAT3 is constitutively activated by aberrant upstream tyrosine kinase activities. Stattic is a small molecule inhibitor of STAT3. It selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2 domain (IC50 = 5.1 μM at 37°C). At 10 μM, stattic induces apoptosis in STAT3-dependent breast cancer (MDA-MB-231 and MDA-MB-435S) cell lines.More related product prices
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