SNS-032
- $25 - $5966
- Product name: SNS-032
- CAS: 345627-80-7
- MF: C17H24N4O2S2
- MW: 380.53
- EINECS:
- MDL Number:MFCD09833875
- Synonyms:BMS-3870032 N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide SNS-032 (BMS-387032);N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamid;SNS-032, >=99%;N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide;BMS-387032;4-Piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-;N-(5-((5-Tert-Butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide
43 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 1mg
- 1unit
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberX7382
- Product descriptionN-[5-[(5-Tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
- Packaging250mg
- Price$1077
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging1mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging50mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging100mg
- Price$440
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging250mg
- Price$1107
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA153280
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
- Packaging1g
- Price$1107
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007075
- Product descriptionBMS-387032 95.00%
- Packaging1MG
- Price$148.05
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007075
- Product descriptionBMS-387032 95.00%
- Packaging5MG
- Price$816.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0007075
- Product descriptionBMS-387032 95.00%
- Packaging1G
- Price$2880.15
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1980
- Product descriptionSNS-032(BMS-387032)
- Packaging100mg
- Price$780
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1980
- Product descriptionSNS-032(BMS-387032)
- Packaging25mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1980
- Product descriptionSNS-032(BMS-387032)
- Packaging10mM(in 1mL DMSO)
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1980
- Product descriptionSNS-032(BMS-387032)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS022470
- Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide ≥99%
- Packaging1mg
- Price$25
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7382 | N-[5-[(5-Tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide | 250mg | $1077 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 1mg | $25 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 5mg | $25 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 10mg | $59 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 50mg | $159 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 100mg | $440 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 250mg | $1107 | 2021-12-16 | Buy |
Ambeed | A153280 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% | 1g | $1107 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007075 | BMS-387032 95.00% | 1MG | $148.05 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007075 | BMS-387032 95.00% | 5MG | $816.75 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0007075 | BMS-387032 95.00% | 1G | $2880.15 | 2021-12-16 | Buy |
ApexBio Technology | A1980 | SNS-032(BMS-387032) | 100mg | $780 | 2021-12-16 | Buy |
ApexBio Technology | A1980 | SNS-032(BMS-387032) | 25mg | $250 | 2021-12-16 | Buy |
ApexBio Technology | A1980 | SNS-032(BMS-387032) | 10mM(in 1mL DMSO) | $95 | 2021-12-16 | Buy |
ApexBio Technology | A1980 | SNS-032(BMS-387032) | 1unit | $28 | 2021-12-16 | Buy |
Arctom | AS022470 | N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide ≥99% | 1mg | $25 | 2021-12-16 | Buy |
Properties
Melting point :171-173 °C
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.33±0.70(Predicted)
color :White to Off-White
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.33±0.70(Predicted)
color :White to Off-White
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity against a panel of 190 kinases (IC50s = >1,000 nM). SNS-032 can block the cell cycle, inhibit transcription, and induce apoptosis in multiple myeloma RPMI-8226 cells with an IC90 value of 0.3 μM. This compound has been shown to induce apoptosis by inhibiting the transcription of the anti-apoptotic proteins, Mcl-1 and XIAP.Related product price
- Olaparib
$28-2147.1 - FLAVOPIRIDOL HYDROCHLORIDE
$27-2220 - 779353-01-4
$28-3728.1
Suppliers and manufacturers
career henan chemical co
Capot Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Chongqing Chemdad Co., Ltd
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
ANHUI WITOP BIOTECH CO., LTD
$0.01 /1KG
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide CAS:345627-80-7
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide CAS:345627-80-7