SB-505124
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- $78 - $410
- Product name: SB-505124
- CAS: 356559-13-2
- MF: C20H22ClN3O2
- MW: 371.87
- EINECS:
- MDL Number:
- Synonyms:TGF-β RI Kinase Inhibitor III;Pyridine, 2-[5-(1,3-benzodioxol-5-yl)-2-(1,1-diMethylethyl)-1H-iMidazol-4-yl]-6-Methyl-, Monohydrochloride;SB-505124 hydrochloride;SB-505124 HCl;TGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem;TGF-β RI Kinase Inhibitor III
6 prices
Selected condition：
Brand
- ApexBio Technology
- Crysdot
- Sigma-Aldrich
- TRC
Package
- 2mg
- 4mg
- 10mg
- 50mg
- ManufacturerApexBio Technology
- Product numberA3799
- Product descriptionSB-505124hydrochloride
- Packaging50mg
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002125
- Product descriptionSB-505124hydrochloride 98+%
- Packaging10mg
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002125
- Product descriptionSB-505124hydrochloride 98+%
- Packaging50mg
- Price$273
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number616453
- Product descriptionTGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem
- Packaging2mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberT338003
- Product descriptionTGF-betaRIKinaseInhibitorIII
- Packaging2mg
- Price$175
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT338003
- Product descriptionTGF-betaRIKinaseInhibitorIII
- Packaging4mg
- Price$280
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | A3799 | SB-505124hydrochloride | 50mg | $410 | 2021-12-16 | Buy |
| Crysdot | CD31002125 | SB-505124hydrochloride 98+% | 10mg | $78 | 2021-12-16 | Buy |
| Crysdot | CD31002125 | SB-505124hydrochloride 98+% | 50mg | $273 | 2021-12-16 | Buy |
| Sigma-Aldrich | 616453 | TGF-β RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem | 2mg | $216 | 2024-03-01 | Buy |
| TRC | T338003 | TGF-betaRIKinaseInhibitorIII | 2mg | $175 | 2021-12-16 | Buy |
| TRC | T338003 | TGF-betaRIKinaseInhibitorIII | 4mg | $280 | 2021-12-16 | Buy |
Properties
storage temp. :2-8°C
solubility :DMSO: 24 mg/mL
form :solid
color :yellow
solubility :DMSO: 24 mg/mL
form :solid
color :yellow
Safety Information
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Description
TGF-β RI Kinase Inhibitor III is a cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of ACTR-IB (activin receptor-like kinase 4, IC50 = 129 nM), TGF β RI (activin receptor-like kinase 5, IC50 = 47 nM), and ACTR-IC (activin receptor-like kinase 7). TGF-β RI Kinase Inhibitor III inhibits p38 MAPKα only at much higher concentrations IC50 = 10.6 βM) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.Related product price
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