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ChemicalBook >> CAS DataBase List >> (S)-(+)-Ibuprofen

(S)-(+)-Ibuprofen

(S)-(+)-Ibuprofen price.
  • $5 - $1732.5
  • Product name: (S)-(+)-Ibuprofen
  • CAS: 51146-56-6
  • MF: C13H18O2
  • MW: 206.28
  • EINECS:610-620-9
  • MDL Number:MFCD00069289
  • Synonyms:(S)-(+)-2-(4-ISOBUTYLPHENYL)PROPIONIC ACID;(S)-(+)-4-ISOBUTYL-ALPHA-METHYLPHENYLACETIC ACID;(S)-(+)-IBUPROFEN;(2s)-2-[4-(2-methylpropyl)phenyl]propionic acid;(S)-(+)-Ibuprofen ReagentPlus(R), 99%;(S)-2-(4-Isobutylphenyl)propanoic acid, 95+%;(S)-((addition))-Ibuprofen;(S)-(+)-4-Isobutyl-a-methylphenylacetic acid
38 prices
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chem-Impex
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  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
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Package
  • 500mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 10MG
  • 100mg
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1kg
  • ManufacturerAK Scientific
  • Product numberO942
  • Product description(S)-(+)-Ibuprofen
  • Packaging5g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10678
  • Product description(S)-(+)-Ibuprofen
  • Packaging100mg
  • Price$19.8
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ90710
  • Product description(S)-(+)-Ibuprofen
  • Packaging25g
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10678
  • Product description(S)-(+)-Ibuprofen
  • Packaging1g
  • Price$36
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging1g
  • Price$8
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging10g
  • Price$13
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging25g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging100g
  • Price$88
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging500g
  • Price$347
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA182774
  • Product description(S)-Ibuprofen 98+%
  • Packaging1kg
  • Price$630
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002281
  • Product descriptionDEXIBUPROFEN 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002281
  • Product descriptionDEXIBUPROFEN 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1018
  • Product description(S)-(+)-Ibuprofen
  • Packaging1g
  • Price$38
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1018
  • Product description(S)-(+)-Ibuprofen
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific O942 (S)-(+)-Ibuprofen 5g $14 2021-12-16 Buy
AK Scientific J10678 (S)-(+)-Ibuprofen 100mg $19.8 2021-12-16 Buy
AK Scientific J90710 (S)-(+)-Ibuprofen 25g $34 2021-12-16 Buy
AK Scientific J10678 (S)-(+)-Ibuprofen 1g $36 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 100mg $5 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 1g $8 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 5g $10 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 10g $13 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 25g $26 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 100g $88 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 500g $347 2021-12-16 Buy
Ambeed A182774 (S)-Ibuprofen 98+% 1kg $630 2021-12-16 Buy
American Custom Chemicals Corporation API0002281 DEXIBUPROFEN 95.00% 100MG $1732.5 2021-12-16 Buy
American Custom Chemicals Corporation API0002281 DEXIBUPROFEN 95.00% 10MG $721.88 2021-12-16 Buy
ApexBio Technology B1018 (S)-(+)-Ibuprofen 1g $38 2021-12-16 Buy
ApexBio Technology B1018 (S)-(+)-Ibuprofen 10mM(in 1mL DMSO) $50 2021-12-16 Buy

Properties

Melting point :49-53 °C(lit.)
alpha :57 º (c=2, EtOH)
Boiling point :285.14°C (rough estimate)
Density :1.0364 (rough estimate)
refractive index :59 ° (C=2, EtOH)
Flash point :>230 °F
storage temp. :Sealed in dry,Room Temperature
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.5 mg/mL
pka :4.41±0.10(Predicted)
form :solid
color :white
optical activity :[α]20/D +59°, c = 2 in ethanol
Water Solubility :insoluble
BRN :3590022
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :HEFNNWSXXWATRW-JTQLQIEISA-N
CAS DataBase Reference :51146-56-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Ibuprofen is a non-steroidal anti-inflammatory drug with diverse biochemical actions, most notably inhibiting COX-1 and COX-2 (IC50s = 2.6 and 1.53, μM, respectively). It is commonly synthesized as a racemic mixture of (S)- and (R)-isomers. (S)-Ibuprofen is an enantiomer that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. (S)-Ibuprofen also inhibits activation of NF-κB more effectively than (R)-ibuprofen (IC50s = 62 and 122 μM, respectively). However, the enantiomers are equipotent in blocking superoxide formation, β-glucuronidase release, and LTB4 generation by stimulated neutrophils (IC50 values range from 0.14 to 0.58 μM). A majority of (R)-ibuprofen can be inverted to (S)-ibuprofen in humans after oral administration.

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