RO 48-8071
|
- $44 - $1500
- Product name: RO 48-8071
- CAS: 189197-69-1
- MF: C23H27BrFNO2.C4H4O4
- MW: 564.45
- EINECS:
- MDL Number:MFCD05865242
- Synonyms:Ro 48-8071 fumarate salt;(4-((6-(allyl(methyl)amino)hexyl)oxy)-2-fluorophenyl)(4-bromophenyl)methanone fumarate Ro48-8071;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone (2E)-2-butenedioate (1:1);OSC Inhibitor, Ro 48-8071 ;Aids163155;Aids-163155;Methanone, (4-bromophenyl)[2-fluoro-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl]-,(2E)-2-butenedioate;(4-Bromophenyl)[2-fluoro-4-[[6-(methyl-2-propen-1-ylamino)hexyl]oxy]phenyl]methanone
22 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4012AH
- Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
- Packaging100mg
- Price$628
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number4012AH
- Product description(4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid
- Packaging5mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67231
- Product descriptionRo 48-8071, 98%
- Packaging10mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging5mg
- Price$44
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging25mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA674342
- Product descriptionRo48-8071fumarate 98+%
- Packaging50mg
- Price$111
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000522
- Product descriptionRO 48-8071 FUMARATE 95.00%
- Packaging25MG
- Price$1270.96
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberLIP0000522
- Product descriptionRO 48-8071 FUMARATE 95.00%
- Packaging5MG
- Price$761.66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4860
- Product descriptionRo48-8071fumarate
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4860
- Product descriptionRo48-8071fumarate
- Packaging10mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4860
- Product descriptionRo48-8071fumarate
- Packaging50mg
- Price$236
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4860
- Product descriptionRo48-8071fumarate
- Packaging100mg
- Price$394
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR103645
- Product descriptionRo 48-8071 fumarate
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR103645
- Product descriptionRo 48-8071 fumarate
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002850
- Product descriptionRo48-8071fumarate 98+%
- Packaging50mg
- Price$248
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4012AH | (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid | 100mg | $628 | 2021-12-16 | Buy |
| AK Scientific | 4012AH | (4-Bromophenyl)-[2-fluoro-4-[6-[methyl(prop-2-enyl)amino]hexoxy]phenyl]methanone,(E)-but-2-enedioicacid | 5mg | $113 | 2021-12-16 | Buy |
| Alfa Aesar | J67231 | Ro 48-8071, 98% | 10mg | $116 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 5mg | $44 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 10mg | $65 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 25mg | $85 | 2021-12-16 | Buy |
| Ambeed | A674342 | Ro48-8071fumarate 98+% | 50mg | $111 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000522 | RO 48-8071 FUMARATE 95.00% | 25MG | $1270.96 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIP0000522 | RO 48-8071 FUMARATE 95.00% | 5MG | $761.66 | 2021-12-16 | Buy |
| ApexBio Technology | B4860 | Ro48-8071fumarate | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B4860 | Ro48-8071fumarate | 10mg | $124 | 2021-12-16 | Buy |
| ApexBio Technology | B4860 | Ro48-8071fumarate | 50mg | $236 | 2021-12-16 | Buy |
| ApexBio Technology | B4860 | Ro48-8071fumarate | 100mg | $394 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR103645 | Ro 48-8071 fumarate | 10mg | $75 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR103645 | Ro 48-8071 fumarate | 50mg | $262.5 | 2021-12-16 | Buy |
| Crysdot | CD31002850 | Ro48-8071fumarate 98+% | 50mg | $248 | 2021-12-16 | Buy |
Properties
Melting point :90-92.7 °C
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :H2O: >5 mg/mL at ~60 °C
form :solid
color :white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Ro 48-8071 fumarate is an orally active 2,3-oxidosqualene lanosterol cyclase (OSC) inhibitor where OSC represents a unique target for a cholesterol-lowering drug. Partial inhibition of OSC should reduce synthesis of lanosterol and subsequent sterols, and also stimulate the production of epoxysterols that repress HMG-CoA reductase expression, generating a synergistic, self-limited negative regulatory loop.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
LEAPCHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited
