Quinine
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- $6 - $4500
- Product name: Quinine
- CAS: 130-95-0
- MF: C20H24N2O2
- MW: 324.42
- EINECS:205-003-2
- MDL Number:MFCD00198096
- Synonyms:(1R)-(6-Methoxyquinolin-4-yl)(5-vinylquinuclidin-2-yl)Methanol;(-)-QUININE FOR RESOLUTION OF RACEMATES;(R)-[(2S,4S,5R)-1-Aza-5-vinylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine, (R)-[(2S,4S,5R)-1-Aza-5-ethenylbicyclo[2.2.2]oct-2-yl](6-methoxyquinolin-4-yl)methanol;Quinine Anhydrous, for Fluorescene;(8R,9S)-Quinidine-d3;(9S)-6'-Methoxycinchonan-9-ol-d3;Chinidin-d3
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Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Ambeed
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
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Package
- 20mg
- 50mg
- 100mg
- 250mg
- 1g
- 5G
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- 25g
- 50g
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- 250g
- 500g
- 1kg
- 10Kg
- ManufacturerAdipogen Life Sciences
- Product numberCDX-Q0012-G005
- Product descriptionQuinine(anhydrous) ≥98%(NMR)
- Packaging5G
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ97276
- Product descriptionQuinine
- Packaging100g
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7113
- Product descriptionQuinine
- Packaging25g
- Price$78
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7113
- Product descriptionQuinine
- Packaging5g
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ97276
- Product descriptionQuinine
- Packaging1g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberA10459
- Product descriptionQuinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine
- Packaging250g
- Price$693.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA10459
- Product descriptionQuinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine
- Packaging50g
- Price$222
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA10459
- Product descriptionQuinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine
- Packaging10g
- Price$67
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA118859
- Product descriptionQuinine 98%
- Packaging10g
- Price$16
- Updated2021-12-16
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- ManufacturerAmbeed
- Product numberA118859
- Product descriptionQuinine 98%
- Packaging100g
- Price$126
- Updated2021-12-16
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- ManufacturerAmbeed
- Product numberA118859
- Product descriptionQuinine 98%
- Packaging500g
- Price$392
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS438595
- Product descriptionQuinine 98%
- Packaging1g
- Price$6
- Updated2021-12-16
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- ManufacturerArctom
- Product numberAS438595
- Product descriptionQuinine 98%
- Packaging5g
- Price$11
- Updated2021-12-16
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- ManufacturerArctom
- Product numberAS438595
- Product descriptionQuinine 98%
- Packaging10g
- Price$15
- Updated2021-12-16
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- ManufacturerArctom
- Product numberCFN90195
- Product descriptionQuinine ≥98%
- Packaging20mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS438595
- Product descriptionQuinine 98%
- Packaging25g
- Price$33
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-Q0012-G005 | Quinine(anhydrous) ≥98%(NMR) | 5G | $56 | 2021-12-16 | Buy |
| AK Scientific | J97276 | Quinine | 100g | $187 | 2021-12-16 | Buy |
| AK Scientific | X7113 | Quinine | 25g | $78 | 2021-12-16 | Buy |
| AK Scientific | X7113 | Quinine | 5g | $33 | 2021-12-16 | Buy |
| AK Scientific | J97276 | Quinine | 1g | $10 | 2021-12-16 | Buy |
| Alfa Aesar | A10459 | Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine | 250g | $693.65 | 2024-03-01 | Buy |
| Alfa Aesar | A10459 | Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine | 50g | $222 | 2024-03-01 | Buy |
| Alfa Aesar | A10459 | Quinine, anhydrous, 99% (total base), may cont. up to 5% dihydroquinine | 10g | $67 | 2024-03-01 | Buy |
| Ambeed | A118859 | Quinine 98% | 10g | $16 | 2021-12-16 | Buy |
| Ambeed | A118859 | Quinine 98% | 100g | $126 | 2021-12-16 | Buy |
| Ambeed | A118859 | Quinine 98% | 500g | $392 | 2021-12-16 | Buy |
| Arctom | AS438595 | Quinine 98% | 1g | $6 | 2021-12-16 | Buy |
| Arctom | AS438595 | Quinine 98% | 5g | $11 | 2021-12-16 | Buy |
| Arctom | AS438595 | Quinine 98% | 10g | $15 | 2021-12-16 | Buy |
| Arctom | CFN90195 | Quinine ≥98% | 20mg | $30 | 2021-12-16 | Buy |
| Arctom | AS438595 | Quinine 98% | 25g | $33 | 2021-12-16 | Buy |
Properties
Melting point :173-175 °C(lit.)
alpha :-172 º (c=1, EtOH)
Boiling point :462.75°C (rough estimate)
Density :1.1294 (rough estimate)
vapor pressure :0Pa at 25℃
refractive index :1.6250 (estimate)
Flash point :>110°C (>230°F)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :H2O: soluble
pka :8.52(at 25℃)
form :Crystalline Powder
color :White
PH :9.0 (0.5g/l, H2O, 20℃)
PH Range :Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)
optical activity :[α]25/D 165°, c = 2 in ethanol
Odor Type :odorless
Water Solubility :slightly soluble
Sensitive :Light Sensitive
Hydrolytic Sensitivity :2: reacts with aqueous acid
Merck :14,8061
BRN :91867
Major Application :Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system
LogP :3.17 at 25℃
CAS DataBase Reference :130-95-0(CAS DataBase Reference)
NIST Chemistry Reference :Quinine(130-95-0)
EPA Substance Registry System :Quinine (130-95-0)
alpha :-172 º (c=1, EtOH)
Boiling point :462.75°C (rough estimate)
Density :1.1294 (rough estimate)
vapor pressure :0Pa at 25℃
refractive index :1.6250 (estimate)
Flash point :>110°C (>230°F)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :H2O: soluble
pka :8.52(at 25℃)
form :Crystalline Powder
color :White
PH :9.0 (0.5g/l, H2O, 20℃)
PH Range :Blue I uorescence (3.0) to weak violet I uorescence (5.0);Weak violet I uorescence (9.5) to nonI uorescence (10.0)
optical activity :[α]25/D 165°, c = 2 in ethanol
Odor Type :odorless
Water Solubility :slightly soluble
Sensitive :Light Sensitive
Hydrolytic Sensitivity :2: reacts with aqueous acid
Merck :14,8061
BRN :91867
Major Application :Bird repellents, sunscreen, antimalarial agent, antiviral agent, antitumor agent, drug-coated coronaryagent, antiparasitic agent, treatment of epilepsy, skeletal muscle spasm, drug-coated coronary stent system
LogP :3.17 at 25℃
CAS DataBase Reference :130-95-0(CAS DataBase Reference)
NIST Chemistry Reference :Quinine(130-95-0)
EPA Substance Registry System :Quinine (130-95-0)
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Quinine, an alkaloid derived from the bark of the cinchona tree, is a blood schizontocidal agent that is more toxic than chloroquine.Quinine is used to treat malaria caused by Plasmodium falciparum. Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.Quinine should not be used to treat or prevent night time leg cramps. This medicine may cause very serious unwanted effects and should only be used for patients with malaria.It is administered parenterally to patients with severe or complicated malaria who cannot take drugs by mouth because of coma, convulsions or vomiting.
It is administered orally to less seriously ill patients with infections likely to be resistant to chloroquine or mefloquine, sometimes in combination with pyrimethamine/sulfadoxine or a tetracycline.
Quinine is an extremely basic compound and is, therefore, always presented as a salt. Various preparations exist, including the hydrochloride, dihydrochloride, sulphate, bisulphate, and gluconate salts; of these the dihydrochloride is the most widely used. Quinine has rapid schizonticidal action against intra-erythrocytic malaria parasites. It is also gametocytocidal for Plasmodium vivax and Plasmodium malariae, but not for Plasmodium falciparum. Quinine also has analgesic, but not antipyretic properties. The anti-malarial mechanism of action of quinine is unknown.
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Suppliers and manufacturers
Guangzhou TongYi biochemistry technology Co.,LTD
