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ChemicalBook >> CAS DataBase List >> Pyocyanine

Pyocyanine

Pyocyanine price.
  • $58 - $1017
  • Product name: Pyocyanine
  • CAS: 85-66-5
  • MF: C13H10N2O
  • MW: 210.23
  • EINECS:
  • MDL Number:MFCD01794662
  • Synonyms:Pyocyanine;1-Oxylato-5-methylphenazin-5-ium;5-Methyl-1(5H)-phenazinone;Sanasin;Sanazin;Pyocyanin, Ready Made Solution from Pseudomonas aeruginosa;pyocyanin;5-methylphenazin-1-one
11 prices
Selected condition:
Brand
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 500μl
  • ManufacturerApexBio Technology
  • Product numberC3822
  • Product descriptionPyocyanin
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3822
  • Product descriptionPyocyanin
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3822
  • Product descriptionPyocyanin
  • Packaging50mg
  • Price$603
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3822
  • Product descriptionPyocyanin
  • Packaging100mg
  • Price$1017
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009594
  • Product descriptionPyocyanin ≥98%
  • Packaging5mg
  • Price$58
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009594
  • Product descriptionPyocyanin ≥98%
  • Packaging10mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009594
  • Product descriptionPyocyanin ≥98%
  • Packaging50mg
  • Price$522
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009594
  • Product descriptionPyocyanin ≥98%
  • Packaging100mg
  • Price$986
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberR9532
  • Product descriptionPyocyanin, Ready Made Solution from Pseudomonas aeruginosa 5?mg/mL in DMSO
  • Packaging500μl
  • Price$119
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0046
  • Product descriptionPyocyanin from
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP0046
  • Product descriptionPyocyanin from
  • Packaging25mg
  • Price$608
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology C3822 Pyocyanin 5mg $95 2021-12-16 Buy
ApexBio Technology C3822 Pyocyanin 10mg $180 2021-12-16 Buy
ApexBio Technology C3822 Pyocyanin 50mg $603 2021-12-16 Buy
ApexBio Technology C3822 Pyocyanin 100mg $1017 2021-12-16 Buy
Cayman Chemical 10009594 Pyocyanin ≥98% 5mg $58 2024-03-01 Buy
Cayman Chemical 10009594 Pyocyanin ≥98% 10mg $110 2024-03-01 Buy
Cayman Chemical 10009594 Pyocyanin ≥98% 50mg $522 2024-03-01 Buy
Cayman Chemical 10009594 Pyocyanin ≥98% 100mg $986 2024-03-01 Buy
Sigma-Aldrich R9532 Pyocyanin, Ready Made Solution from Pseudomonas aeruginosa 5?mg/mL in DMSO 500μl $119 2024-03-01 Buy
Sigma-Aldrich P0046 Pyocyanin from 5mg $120 2024-03-01 Buy
Sigma-Aldrich P0046 Pyocyanin from 25mg $608 2024-03-01 Buy

Properties

Melting point :133°
Boiling point :349.76°C (rough estimate)
Density :1.1427 (rough estimate)
refractive index :1.5300 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :solid
pka :2.42±0.20(Predicted)
color :Dark blue
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

P. aeruginosa is a common pathogen affecting immunocompromised patients with acute diseases such as pneumonia and vasculitis or chronic diseases such as cystic fibrosis. It produces several phenazine toxic metabolites, in which the most predominant is a blue pigment, pyocyanin. Pyocyanin has been shown to accelerate neutrophil apoptosis in vitro, resulting in resolution of acute inflammation, that is beneficial for bacterial survival. It also induces a 10-fold acceleration of neutrophil apoptosis in vitro. Pyocyanin production results in reduced bacterial clearance from the lungs of immunocompromised patients. It has also been reported to induce apoptosis in human lung epithelial cells and to induce premature cellular senescence in mammalian cells. Pyocyanin undergoes nonenzymatic reduction by NADPH, which produces hydrogen peroxide and depletes intracellular glutathione levels, causing oxidative stress in susceptible cells.

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