PF 04418948
- $48 - $2200
- Product name: PF 04418948
- CAS: 1078166-57-0
- MF: C23H20FNO5
- MW: 409.41
- EINECS:
- MDL Number:MFCD24387541
- Synonyms:1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid;PF 04418948;1-(4-FLUOROBENZOYL)-3-[(6-METHOXYNAPHTHALEN-2-YL)OXYMETHYL]AZETIDINE-3-CARBOXYLIC ACID;PF-04418948;PF04418948;PF 04418948;CS-2852;PF-0441848;PF04418948; PF 04418948;3-Azetidinecarboxylic acid, 1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-
24 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 50
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2831DC
- Product descriptionPF-04418948
- Packaging10mg
- Price$262
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging5mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging25mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging50mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging100mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging250mg
- Price$705
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging1g
- Price$1762
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5726
- Product descriptionPF04418948
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5726
- Product descriptionPF04418948
- Packaging50mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15016
- Product descriptionPF-04418948 ≥98%
- Packaging5mg
- Price$98
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15016
- Product descriptionPF-04418948 ≥98%
- Packaging10mg
- Price$146
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15016
- Product descriptionPF-04418948 ≥98%
- Packaging50mg
- Price$680
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15016
- Product descriptionPF-04418948 ≥98%
- Packaging100mg
- Price$964
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5011
- Product descriptionPF-04418948 99.22%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5011
- Product descriptionPF-04418948 99.22%
- Packaging10mg
- Price$110
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2831DC | PF-04418948 | 10mg | $262 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 5mg | $48 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 10mg | $75 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 25mg | $158 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 50mg | $272 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 100mg | $353 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 250mg | $705 | 2021-12-16 | Buy |
Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 1g | $1762 | 2021-12-16 | Buy |
ApexBio Technology | B5726 | PF04418948 | 10mg | $85 | 2021-12-16 | Buy |
ApexBio Technology | B5726 | PF04418948 | 50mg | $350 | 2021-12-16 | Buy |
Cayman Chemical | 15016 | PF-04418948 ≥98% | 5mg | $98 | 2024-03-01 | Buy |
Cayman Chemical | 15016 | PF-04418948 ≥98% | 10mg | $146 | 2024-03-01 | Buy |
Cayman Chemical | 15016 | PF-04418948 ≥98% | 50mg | $680 | 2024-03-01 | Buy |
Cayman Chemical | 15016 | PF-04418948 ≥98% | 100mg | $964 | 2024-03-01 | Buy |
ChemScene | CS-5011 | PF-04418948 99.22% | 5mg | $70 | 2021-12-16 | Buy |
ChemScene | CS-5011 | PF-04418948 99.22% | 10mg | $110 | 2021-12-16 | Buy |
Properties
Melting point :171-172°C
Boiling point :639.1±55.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.25±0.20(Predicted)
color :white to beige
InChIKey :POJZIZBONPAWIV-UHFFFAOYSA-N
Boiling point :639.1±55.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.25±0.20(Predicted)
color :white to beige
InChIKey :POJZIZBONPAWIV-UHFFFAOYSA-N
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Prostaglandin E2 (PGE2) evokes distinct responses through four different ‘E prostanoid’ (EP) receptors. EP2 is a G protein-coupled receptor which signals preferentially through Gs proteins. PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). It is over a thousand-fold less active at other prostanoid receptors, including other EP receptors. PF-04418948 can be used in cells and tissues. In rats, it significantly reduces the effects of the EP2-selective agonist butaprost on cutaneous blood flow when given orally.More related product prices
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