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ChemicalBook >> CAS DataBase List >> Olodaterol

Olodaterol

Olodaterol price.
  • $56 - $1700
  • Product name: Olodaterol
  • CAS: 868049-49-4
  • MF: C21H26N2O5
  • MW: 386.44
  • EINECS:813-858-3
  • MDL Number:MFCD16619349
  • Synonyms:6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-;BI 1744(Olodaterol;Striverdi Respimat);Olodaterol;Olodaterol ImpurityＡ 　;BI-1744;Striverdi
14 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • DC Chemicals
Package
  • 1mg
  • 2mg
  • 5MG
  • 10mg
  • 25mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number4736BB
  • Product descriptionOlodaterol
  • Packaging2mg
  • Price$171
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014046
  • Product descriptionOLODATEROL 95.00%
  • Packaging5MG
  • Price$501.28
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging1mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging2mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFH152793
  • Product descriptionOlodaterol
  • Packaging25mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging1mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging5mg
  • Price$289
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging10mg
  • Price$490
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21794
  • Product descriptionOlodaterol ≥98%
  • Packaging25mg
  • Price$1113
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM255429
  • Product description(R)-6-Hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95%
  • Packaging100mg
  • Price$673
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10384
  • Product descriptionOlodaterol >98%
  • Packaging250mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10384
  • Product descriptionOlodaterol >98%
  • Packaging1g
  • Price$1700
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4736BB Olodaterol 2mg $171 2021-12-16 Buy
American Custom Chemicals Corporation API0014046 OLODATEROL 95.00% 5MG $501.28 2021-12-16 Buy
Biosynth Carbosynth FH152793 Olodaterol 1mg $56 2021-12-16 Buy
Biosynth Carbosynth FH152793 Olodaterol 2mg $90 2021-12-16 Buy
Biosynth Carbosynth FH152793 Olodaterol 5mg $160 2021-12-16 Buy
Biosynth Carbosynth FH152793 Olodaterol 10mg $250 2021-12-16 Buy
Biosynth Carbosynth FH152793 Olodaterol 25mg $325 2021-12-16 Buy
Cayman Chemical 21794 Olodaterol ≥98% 1mg $89 2024-03-01 Buy
Cayman Chemical 21794 Olodaterol ≥98% 5mg $289 2024-03-01 Buy
Cayman Chemical 21794 Olodaterol ≥98% 10mg $490 2024-03-01 Buy
Cayman Chemical 21794 Olodaterol ≥98% 25mg $1113 2024-03-01 Buy
Chemenu CM255429 (R)-6-Hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95% 100mg $673 2021-12-16 Buy
DC Chemicals DC10384 Olodaterol >98% 250mg $850 2021-12-16 Buy
DC Chemicals DC10384 Olodaterol >98% 1g $1700 2021-12-16 Buy

Properties

Boiling point :649.0±55.0 °C(Predicted)
Density :1.250
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :9.42±0.20(Predicted)
color :Light yellow to khaki
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

In 2013, olodaterol (also known BI-1744 CL) was approved for the treatment of chronic obstructive pulmonary disease (COPD) in Russia (March), Canada (June), and the EuropeanUnion (October). Olodaterol is delivered via the Respimat? Soft Mist? inhaler. Olodaterol was discovered from an effort to identify a β2-adrenergic receptor agonist that could be given once daily and with a superior safety profile over known β2- adrenergic receptor agonists. Olodaterol is a potent β2 agonist (EC50=0.1 nM, intrinsic activity=88%) and is highly selective for the β2 receptor over β1 and β3 receptors. In preclinical models in guinea pigs and dogs, olodaterol had a rapid onset of action and provided bronchoprotection over 24 h. Mechanistic studies indicated that olodaterol forms a highly stable complex with the β2-adrenergic receptor, with a dissociation half-life of 17.8 h. The synthesis of olodaterol proceeds through an (R)-styrene epoxide that is prepared via enantioselective reduction of an α-chloroketone intermediate. Ring opening of the epoxide with 1-(4- methoxyphenyl)-2-methylpropan-2-amine provides olodaterol.