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ChemicalBook >> CAS DataBase List >> Obatoclax mesilate

Obatoclax mesilate

Obatoclax mesilate price.
  • $62 - $6615
  • Product name: Obatoclax mesilate
  • CAS: 803712-79-0
  • MF: C20H19N3O.CH4O3S
  • MW: 413.49
  • EINECS:804-325-6
  • MDL Number:MFCD18074508
  • Synonyms:OBATOCLAX MESYLATE;2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate;Obatoclax mesilate;1H-Indole, 2-(2-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-, monomethanesulfonate;Gx 15-070;Gx 15-070ms;Gx015-070;Unii-39200fj43j
33 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Tocris
  • TRC
Package
  • 2mg
  • 10
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
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  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberV2454
  • Product descriptionObatoclaxmesylate
  • Packaging10mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010349
  • Product descriptionOBATOCLAX MESYLATE 95.00%
  • Packaging5MG
  • Price$276.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4194
  • Product descriptionObatoclaxmesylate(GX15-070)
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4194
  • Product descriptionObatoclaxmesylate(GX15-070)
  • Packaging50mg
  • Price$494
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60207
  • Product descriptionObatoclaxMesylate(GX15-070) ≥98%
  • Packaging10mg
  • Price$288
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546091
  • Product descriptionObatoclax (GX15-070) >98%
  • Packaging5mg
  • Price$190.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546091
  • Product descriptionObatoclax (GX15-070) >98%
  • Packaging25mg
  • Price$515.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181072
  • Product descriptionObatoclax (GX15-070) >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181072
  • Product descriptionObatoclax (GX15-070) >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181072
  • Product descriptionObatoclax (GX15-070) >98%
  • Packaging1000mg
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO32672
  • Product descriptionObatoclax mesylate
  • Packaging25mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO32672
  • Product descriptionObatoclax mesylate
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO32672
  • Product descriptionObatoclax mesylate
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO32672
  • Product descriptionObatoclax mesylate
  • Packaging2mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO32672
  • Product descriptionObatoclax mesylate
  • Packaging1mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11499
  • Product descriptionObatoclax (mesylate) ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific V2454 Obatoclaxmesylate 10mg $132 2021-12-16 Buy
American Custom Chemicals Corporation API0010349 OBATOCLAX MESYLATE 95.00% 5MG $276.1 2021-12-16 Buy
ApexBio Technology A4194 Obatoclaxmesylate(GX15-070) 5mg $100 2021-12-16 Buy
ApexBio Technology A4194 Obatoclaxmesylate(GX15-070) 50mg $494 2021-12-16 Buy
Arctom CFN60207 ObatoclaxMesylate(GX15-070) ≥98% 10mg $288 2021-12-16 Buy
Biorbyt Ltd orb546091 Obatoclax (GX15-070) >98% 5mg $190.4 2021-12-16 Buy
Biorbyt Ltd orb546091 Obatoclax (GX15-070) >98% 25mg $515.1 2021-12-16 Buy
Biorbyt Ltd orb181072 Obatoclax (GX15-070) >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181072 Obatoclax (GX15-070) >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb181072 Obatoclax (GX15-070) >98% 1000mg $2839 2021-12-16 Buy
Biosynth Carbosynth FO32672 Obatoclax mesylate 25mg $450 2021-12-16 Buy
Biosynth Carbosynth FO32672 Obatoclax mesylate 10mg $300 2021-12-16 Buy
Biosynth Carbosynth FO32672 Obatoclax mesylate 5mg $200 2021-12-16 Buy
Biosynth Carbosynth FO32672 Obatoclax mesylate 2mg $120 2021-12-16 Buy
Biosynth Carbosynth FO32672 Obatoclax mesylate 1mg $75 2021-12-16 Buy
Cayman Chemical 11499 Obatoclax (mesylate) ≥98% 1mg $62 2024-03-01 Buy

Properties

storage temp. :-20°C
solubility :Soluble in DMSO (up to 5 mg/ml).
form :solid
color :Purple
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. Obstoclax also induces autophagy in mouse embryo fibroblasts and in HeLa cells. This compound inhibits the growth of cancer cell lines and primary cancer isolates.

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