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ChemicalBook >> CAS DataBase List >> ONO-AE3-208

ONO-AE3-208

ONO-AE3-208 price.
  • $44 - $2958
  • Product name: ONO-AE3-208
  • CAS: 402473-54-5
  • MF: C24H21FN2O3
  • MW: 404.43
  • EINECS:
  • MDL Number:MFCD13184814
  • Synonyms:4-Cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]Benzenebutanoic acid;ONO-AE3-208;AE 3-208;ONO-AE3-208;AE 3-208;ONO AE3 208;AE 3-208;ONO AE3 208;Benzenebutanoic acid, 4-cyano-2-[[2-(4-fluoro-1-naphthalenyl)-1-oxopropyl]amino]-;4-(4-cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoic acid;4-{4-Cyano-2-[2-(4-fluoro-naphthalen-1-yl)-propionylamino]-phenyl}-butyric acid
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  • AK Scientific
  • Ambeed
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  • ApexBio Technology
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  • Chemenu
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  • Sigma-Aldrich
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  • 1g
  • ManufacturerAK Scientific
  • Product number3952AH
  • Product description4-(4-Cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoicacid
  • Packaging10mg
  • Price$284
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging2mg
  • Price$63
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging5mg
  • Price$82
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging10mg
  • Price$130
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging50mg
  • Price$537
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging100mg
  • Price$755
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging250mg
  • Price$1129
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA187661
  • Product descriptionONO-AE3-208 98+%
  • Packaging1g
  • Price$2958
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000640
  • Product descriptionONO-AE3-208 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000640
  • Product descriptionONO-AE3-208 95.00%
  • Packaging5MG
  • Price$499.77
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3684
  • Product descriptionONO-AE3-208
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA3684
  • Product descriptionONO-AE3-208
  • Packaging10mg
  • Price$220
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  • ManufacturerApexBio Technology
  • Product numberA3684
  • Product descriptionONO-AE3-208
  • Packaging25mg
  • Price$450
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number14522
  • Product descriptionONO-AE3-208 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number14522
  • Product descriptionONO-AE3-208 ≥98%
  • Packaging5mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14522
  • Product descriptionONO-AE3-208 ≥98%
  • Packaging10mg
  • Price$214
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3952AH 4-(4-Cyano-2-(2-(4-fluoronaphthalen-1-yl)propanamido)phenyl)butanoicacid 10mg $284 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 2mg $63 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 5mg $82 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 10mg $130 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 50mg $537 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 100mg $755 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 250mg $1129 2021-12-16 Buy
Ambeed A187661 ONO-AE3-208 98+% 1g $2958 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000640 ONO-AE3-208 95.00% 1MG $148.05 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000640 ONO-AE3-208 95.00% 5MG $499.77 2021-12-16 Buy
ApexBio Technology A3684 ONO-AE3-208 5mg $130 2021-12-16 Buy
ApexBio Technology A3684 ONO-AE3-208 10mg $220 2021-12-16 Buy
ApexBio Technology A3684 ONO-AE3-208 25mg $450 2021-12-16 Buy
Cayman Chemical 14522 ONO-AE3-208 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 14522 ONO-AE3-208 ≥98% 5mg $130 2024-03-01 Buy
Cayman Chemical 14522 ONO-AE3-208 ≥98% 10mg $214 2024-03-01 Buy

Properties

Boiling point :662.4±55.0 °C(Predicted)
Density :1.30
storage temp. :-20°C
solubility :≥40.4 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥8.1 mg/mL in EtOH with gentle warming and ultrasonic
pka :4.69±0.10(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ONO-AE3-208 is an antagonist of the EP4 receptor (Ki = 1.3 nM) which less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors. In wild type mice, it mimics deletion of EP4 by producing severe colitis, with epithelial loss, crypt damage, and inflammation, after treatment with 3% dextran sodium sulfate. ONO-AE3-208 has also been used to implicate EP4 signaling in immune and autoimmune responses, inflammation, and cancer.

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