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ChemicalBook >> CAS DataBase List >> Nadifloxacin

Nadifloxacin

Nadifloxacin price.
  • $14 - $818
  • Product name: Nadifloxacin
  • CAS: 124858-35-1
  • MF: C19H21FN2O4
  • MW: 360.38
  • EINECS:638-863-6
  • MDL Number:MFCD00865081
  • Synonyms:NDFX;Nadifiloxacin;NadifloxacinAPI;7-fluoro-8-(4-hydroxypiperidin-1-yl)-12-Methyl-4-oxo-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid;9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid;NADIFLOXACIN;9-Fluoro-6,7-dihydro-8-(4-hydroxy-1-piperidinyl)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic Acid;Acuati
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  • AHH
  • AK Scientific
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  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
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Package
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  • 10g
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  • ManufacturerAHH
  • Product numberAPI-1096
  • Product descriptionNadifloxacin 98%
  • Packaging1g
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberH946
  • Product descriptionNadifloxacin
  • Packaging1g
  • Price$81
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging50mg
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging100mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging250mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging1g
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging5g
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging10g
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA140688
  • Product description9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+%
  • Packaging25g
  • Price$818
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003479
  • Product descriptionNADIFLOXACIN 95.00%
  • Packaging10MG
  • Price$411.84
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003479
  • Product descriptionNADIFLOXACIN 95.00%
  • Packaging25MG
  • Price$429.6
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003479
  • Product descriptionNADIFLOXACIN 95.00%
  • Packaging100MG
  • Price$489
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS003066
  • Product descriptionNadifloxacin ≥98%
  • Packaging50mg
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS003066
  • Product descriptionNadifloxacin ≥98%
  • Packaging100mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS003066
  • Product descriptionNadifloxacin ≥98%
  • Packaging250mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS003066
  • Product descriptionNadifloxacin ≥98%
  • Packaging1g
  • Price$71
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH API-1096 Nadifloxacin 98% 1g $560 2021-12-16 Buy
AK Scientific H946 Nadifloxacin 1g $81 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 50mg $14 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 100mg $26 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 250mg $39 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 1g $72 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 5g $235 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 10g $390 2021-12-16 Buy
Ambeed A140688 9-Fluoro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylicacid 98+% 25g $818 2021-12-16 Buy
American Custom Chemicals Corporation API0003479 NADIFLOXACIN 95.00% 10MG $411.84 2021-12-16 Buy
American Custom Chemicals Corporation API0003479 NADIFLOXACIN 95.00% 25MG $429.6 2021-12-16 Buy
American Custom Chemicals Corporation API0003479 NADIFLOXACIN 95.00% 100MG $489 2021-12-16 Buy
Arctom AS003066 Nadifloxacin ≥98% 50mg $14 2021-12-16 Buy
Arctom AS003066 Nadifloxacin ≥98% 100mg $26 2021-12-16 Buy
Arctom AS003066 Nadifloxacin ≥98% 250mg $39 2021-12-16 Buy
Arctom AS003066 Nadifloxacin ≥98% 1g $71 2021-12-16 Buy

Properties

Melting point :245-2470C (dec)
Boiling point :624.9±55.0 °C(Predicted)
Density :1.46±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Sparingly, Heated)
form :White to yellow crystalline solid.
pka :5.55±0.40(Predicted)
color :White to Off-White
Merck :14,6345
InChI :InChI=1S/C19H21FN2O4/c1-10-2-3-12-16-13(18(24)14(19(25)26)9-22(10)16)8-15(20)17(12)21-6-4-11(23)5-7-21/h8-11,23H,2-7H2,1H3,(H,25,26)
InChIKey :JYJTVFIEFKZWCJ-UHFFFAOYSA-N
SMILES :C12=CC(F)=C(N3CCC(O)CC3)C3=C1N(C(C)CC3)C=C(C(O)=O)C2=O
CAS DataBase Reference :124858-35-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes. Studies suggest that the mechanism of inhibition occurs by interfering with DNA replication. Specifically Nadifloxacin suppresses gram-positive bacterial growth by targeting topoisomerase IV and suppresses gram-negative bacteria by inhibiting Topo II (DNA gyrase), which both function to relax postive supercoils before DNA replication. Furthermore, Nadifloxacin can decrease superoxide radical anions such as O2- and OH-, produced by neutrophils.

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