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ChemicalBook >> CAS DataBase List >> NSC59984

NSC59984

NSC59984 price.
  • $28 - $3978
  • Product name: NSC59984
  • CAS: 803647-40-7
  • MF: C12H15N3O4
  • MW: 265.27
  • EINECS:
  • MDL Number:MFCD29905462
  • Synonyms:NSC59984,NCI59984;NSC59984;1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one;CS-2317;NSC-59984;NSC 59984;NCI59984;1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one;NSC-59984,inhibit,Inhibitor,NSC59984,MDM-2/p53,NSC 59984
41 prices
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Brand
  • aablocks
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • Manufactureraablocks
  • Product numberAA00G3P1
  • Product descriptionNSC59984 ≥98%
  • Packaging1mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3P1
  • Product descriptionNSC59984 ≥98%
  • Packaging5mg
  • Price$137
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00G3P1
  • Product descriptionNSC59984 ≥98%
  • Packaging10mg
  • Price$207
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging2mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging5mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging10mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging50mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA661348
  • Product descriptionNSC59984 98+%
  • Packaging1g
  • Price$3978
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPO0001428
  • Product descriptionNSC-59984 95.00%
  • Packaging5MG
  • Price$502.93
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6045
  • Product descriptionNSC59984
  • Packaging2mg
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6045
  • Product descriptionNSC59984
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6045
  • Product descriptionNSC59984
  • Packaging10mg
  • Price$315
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6045
  • Product descriptionNSC59984
  • Packaging50mg
  • Price$1260
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6045
  • Product descriptionNSC59984
  • Packaging100mg
  • Price$2205
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS296010
  • Product descriptionNSC59984 ≥98%
  • Packaging2mg
  • Price$28
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00G3P1 NSC59984 ≥98% 1mg $82 2021-12-16 Buy
aablocks AA00G3P1 NSC59984 ≥98% 5mg $137 2021-12-16 Buy
aablocks AA00G3P1 NSC59984 ≥98% 10mg $207 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 2mg $59 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 5mg $106 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 10mg $138 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 25mg $180 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 50mg $234 2021-12-16 Buy
Ambeed A661348 NSC59984 98+% 1g $3978 2021-12-16 Buy
American Custom Chemicals Corporation APO0001428 NSC-59984 95.00% 5MG $502.93 2021-12-16 Buy
ApexBio Technology B6045 NSC59984 2mg $126 2021-12-16 Buy
ApexBio Technology B6045 NSC59984 5mg $189 2021-12-16 Buy
ApexBio Technology B6045 NSC59984 10mg $315 2021-12-16 Buy
ApexBio Technology B6045 NSC59984 50mg $1260 2021-12-16 Buy
ApexBio Technology B6045 NSC59984 100mg $2205 2021-12-16 Buy
Arctom AS296010 NSC59984 ≥98% 2mg $28 2021-12-16 Buy

Properties

Boiling point :451.8±45.0 °C(Predicted)
Density :1.304±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml)
form :solid
pka :6.72±0.10(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NSC59984 (803647-40-7) is a p53 activator.? Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein degradation via MDM2 and ubiquitin-proteasome pathway. Induces p73-dependent cell death in cancer cells without toxicity toward normal cells.1?Inhibition of p53-MDM2 interaction remains a viable strategy for cancer therapeutic development.2,3

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