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ChemicalBook >> CAS DataBase List >> NOVOBIOCIN SODIUM SALT

NOVOBIOCIN SODIUM SALT

NOVOBIOCIN SODIUM SALT price.
  • $7 - $1910
  • Product name: NOVOBIOCIN SODIUM SALT
  • CAS: 1476-53-5
  • MF: C31H37N2NaO11
  • MW: 636.63
  • EINECS:216-023-6
  • MDL Number:MFCD30207859
  • Synonyms:albamycin(capsule) ;Albamycinsodium ;Cathomycinsodium ;Cathomycinsodiumlyovac ;Monosodiumnovobiocin ;Novobiocin,sodiumderiv. ;Novobiocinmonosodium ;N-[7-[(3-O-Carbamoyl-4-O,5-C-dimethyl-6-deoxy-β-L-lyxo-hexopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-sodiooxy-3-(3-methyl-2-butenyl)benzamide
32 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
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  • 1g
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  • 10g
  • 25g
  • 50ml
  • 100g
  • 100ml
  • 10vial
  • ManufacturerAK Scientific
  • Product numberX5037
  • Product descriptionNovobiocin sodium
  • Packaging5g
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60928
  • Product descriptionNovobiocin sodium salt
  • Packaging1g
  • Price$47.9
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60928
  • Product descriptionNovobiocin sodium salt
  • Packaging5g
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67381
  • Product descriptionNovobiocin sodium salt, 20 mg/ml in distilled water, sterile-filtered
  • Packaging50ml
  • Price$207.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60928
  • Product descriptionNovobiocin sodium salt
  • Packaging10g
  • Price$318
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67381
  • Product descriptionNovobiocin sodium salt, 20 mg/ml in distilled water sterile-filtered
  • Packaging100ml
  • Price$321
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging1mg
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging5mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging25mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging100mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging250mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA299620
  • Product descriptionSodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+%
  • Packaging1g
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18457
  • Product descriptionNovobiocin (sodium salt) ≥95%
  • Packaging1g
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18457
  • Product descriptionNovobiocin (sodium salt) ≥95%
  • Packaging5g
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18457
  • Product descriptionNovobiocin (sodium salt) ≥95%
  • Packaging10g
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2531
  • Product descriptionNovobiocin sodium 99.12%
  • Packaging100mg
  • Price$108
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X5037 Novobiocin sodium 5g $320 2021-12-16 Buy
Alfa Aesar J60928 Novobiocin sodium salt 1g $47.9 2024-03-01 Buy
Alfa Aesar J60928 Novobiocin sodium salt 5g $155 2024-03-01 Buy
Alfa Aesar J67381 Novobiocin sodium salt, 20 mg/ml in distilled water, sterile-filtered 50ml $207.65 2024-03-01 Buy
Alfa Aesar J60928 Novobiocin sodium salt 10g $318 2024-03-01 Buy
Alfa Aesar J67381 Novobiocin sodium salt, 20 mg/ml in distilled water sterile-filtered 100ml $321 2024-03-01 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 1mg $7 2021-12-16 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 5mg $16 2021-12-16 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 25mg $37 2021-12-16 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 100mg $85 2021-12-16 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 250mg $125 2021-12-16 Buy
Ambeed A299620 Sodium4-((7-(((2R,3R,4S,5R)-4-(carbamoyloxy)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl)-2-(3-methylbut-2-en-1-yl)phenolate 98+% 1g $316 2021-12-16 Buy
Cayman Chemical 18457 Novobiocin (sodium salt) ≥95% 1g $44 2024-03-01 Buy
Cayman Chemical 18457 Novobiocin (sodium salt) ≥95% 5g $143 2024-03-01 Buy
Cayman Chemical 18457 Novobiocin (sodium salt) ≥95% 10g $286 2024-03-01 Buy
ChemScene CS-2531 Novobiocin sodium 99.12% 100mg $108 2021-12-16 Buy

Properties

Melting point :215-220 C
alpha :D24 -38° (c = 2.5 in 95% ethanol); D24 -33° (c = 2.5 in water)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: soluble50mg/mL
form :White to yellow solid
color :white to faintly beige
PH :7.5 (100g/l, H2O, 25℃)
optical activity :[α]20/D 48±3°, c = 1% in ethanol
Water Solubility :Soluble in water at 100mg/ml. Also soluble in ethanol or DMSOSoluble in water, ethanol, dimethyldulfoxide and methanol.
Merck :13,6755
BRN :3892910
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Novobiocin is a coumarin antibiotic, first isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the ATPase reaction catalyzed by the GyrB subunit. In addition to permitting relaxation of negative supercoils, novobiocin has been used to generate positively supercoiled DNA. It has also been shown to inhibit the chaperone activity of Hsp90.

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