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ChemicalBook >> CAS DataBase List >> Milrinone

Milrinone

Milrinone price.
  • $5 - $1728
  • Product name: Milrinone
  • CAS: 78415-72-2
  • MF: C12H9N3O
  • MW: 211.22
  • EINECS:278-903-6
  • MDL Number:MFCD00133539
  • Synonyms:Corotrope;Milrila;3-CYANO-6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE;6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE-3-CARBONITRILE;1,6-DIHYDRO-2-METHYL-6-OXO-(3,4'-BIPYRIDINE)-5-CARBONITRILE;6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile;YM-018;2-Oxo-5-(4-pyridyl)-6-methyl-1,2-dihydropyridine-3-carbonitrile
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Brand
  • Abosyn
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
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  • TCI Chemical
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Package
  • 10
  • 5mg
  • 10mg
  • 25MG
  • 10mM(in 1mL DMSO)
  • 50mg
  • 50
  • 100mg
  • 250mg
  • 0.5g
  • 500mg
  • 1g
  • 5g
  • 25g
  • 100g
  • ManufacturerAbosyn
  • Product number61-11777
  • Product description2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98%
  • Packaging1g
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAbosyn
  • Product number61-11777
  • Product description2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98%
  • Packaging5g
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1619
  • Product descriptionMilrinone 98%
  • Packaging0.5g
  • Price$795
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberD270
  • Product descriptionMilrinone
  • Packaging500mg
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberD270
  • Product descriptionMilrinone
  • Packaging5g
  • Price$1728
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62659
  • Product descriptionMilrinone, 98+%
  • Packaging10mg
  • Price$143.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ62659
  • Product descriptionMilrinone, 98+%
  • Packaging50mg
  • Price$527.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ62659
  • Product descriptionMilrinone, 98+%
  • Packaging100mg
  • Price$786
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging250mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging1g
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging5g
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging25g
  • Price$208
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA218047
  • Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
  • Packaging100g
  • Price$708
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003394
  • Product descriptionMilrinone 95.00%
  • Packaging100MG
  • Price$693.92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003394
  • Product descriptionMilrinone 95.00%
  • Packaging25MG
  • Price$140.7
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-11777 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98% 1g $190 2021-12-16 Buy
Abosyn 61-11777 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98% 5g $590 2021-12-16 Buy
AHH API-1619 Milrinone 98% 0.5g $795 2021-12-16 Buy
AK Scientific D270 Milrinone 500mg $248 2021-12-16 Buy
AK Scientific D270 Milrinone 5g $1728 2021-12-16 Buy
Alfa Aesar J62659 Milrinone, 98+% 10mg $143.65 2024-03-01 Buy
Alfa Aesar J62659 Milrinone, 98+% 50mg $527.65 2024-03-01 Buy
Alfa Aesar J62659 Milrinone, 98+% 100mg $786 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 50mg $5 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 250mg $10 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 1g $24 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 5g $58 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 25g $208 2021-12-16 Buy
Ambeed A218047 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% 100g $708 2021-12-16 Buy
American Custom Chemicals Corporation API0003394 Milrinone 95.00% 100MG $693.92 2021-12-16 Buy
American Custom Chemicals Corporation API0003394 Milrinone 95.00% 25MG $140.7 2021-12-16 Buy

Properties

Melting point :>3000C
Boiling point :350.9°C (rough estimate)
Density :1.1922 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :powder
pka :7.21±0.10(Predicted)
color :off-white
Water Solubility :Soluble in DMSO. Insoluble in water.
Merck :14,6197
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :FYEJSUDMDUIMKJ-UHFFFAOYSA-N
CAS DataBase Reference :78415-72-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

Phosphodiesterase 3 (PDE3) family members have high-affinities for both cAMP and cGMP and show cGMP-dependent inhibition of cAMP hydrolysis. Milrinone is a potent inhibitor of type 3 phosphodiesterases (PDEs), inhibiting recombinant PDE3A and PDE3B with IC50 values of 0.45 and 1.0 μM, respectively. It less effectively inhibits other PDE isoforms, with IC50 values of 263, >300, 17.5, 49.1, and 58.3 μM for PDE1, PDE2, PDE4, PDE5, and PDE7, respectively. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.

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