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ChemicalBook >> CAS DataBase List >> LY2109761

LY2109761

LY2109761 price.
  • $28 - $2691.1
  • Product name: LY2109761
  • CAS: 700874-71-1
  • MF: C26H27N5O2
  • MW: 441.52
  • EINECS:
  • MDL Number:MFCD12923354
  • Synonyms:LY2109761/LY-2109761;LY2109761;Quinoline, 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-Morpholinyl)ethoxy]-;4-[5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline;LY210976;4-[2-[4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl]oxyethyl]Morpholine;N-CYCLOPENTYL-WEI -ALANINE;N-CYCLOPENTYL-Β-ALANINE
32 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
  • Usbiological
Package
  • 1unit
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY0460
  • Product description4-[2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine
  • Packaging1mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0460
  • Product description4-[2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine
  • Packaging5mg
  • Price$157
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001403
  • Product description7-(2-MORPHOLINOETHOXY)-4-(2-(PYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE 95.00%
  • Packaging1MG
  • Price$165.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001403
  • Product description7-(2-MORPHOLINOETHOXY)-4-(2-(PYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE 95.00%
  • Packaging5MG
  • Price$498.6
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8464
  • Product descriptionLY2109761
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60192
  • Product descriptionLY2109761
  • Packaging10mg
  • Price$428
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181051
  • Product descriptionLY-2109761 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181051
  • Product descriptionLY-2109761 >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181051
  • Product descriptionLY-2109761 >98%
  • Packaging1000mg
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15409
  • Product descriptionLY2109761 ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15409
  • Product descriptionLY2109761 ≥98%
  • Packaging5mg
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15409
  • Product descriptionLY2109761 ≥98%
  • Packaging10mg
  • Price$176
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM146238
  • Product description4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine 98%
  • Packaging50mg
  • Price$493
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0571
  • Product descriptionLY2109761 99.95%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0571
  • Product descriptionLY2109761 99.95%
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0571
  • Product descriptionLY2109761 99.95%
  • Packaging50mg
  • Price$430
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0460 4-[2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine 1mg $99 2021-12-16 Buy
AK Scientific Y0460 4-[2-[4-(2-Pyridin-2-yl-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl)quinolin-7-yl]oxyethyl]morpholine 5mg $157 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001403 7-(2-MORPHOLINOETHOXY)-4-(2-(PYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE 95.00% 1MG $165.9 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001403 7-(2-MORPHOLINOETHOXY)-4-(2-(PYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE 95.00% 5MG $498.6 2021-12-16 Buy
ApexBio Technology A8464 LY2109761 1unit $28 2021-12-16 Buy
Arctom CFN60192 LY2109761 10mg $428 2021-12-16 Buy
Biorbyt Ltd orb181051 LY-2109761 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb181051 LY-2109761 >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb181051 LY-2109761 >98% 1000mg $2691.1 2021-12-16 Buy
Cayman Chemical 15409 LY2109761 ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 15409 LY2109761 ≥98% 5mg $99 2024-03-01 Buy
Cayman Chemical 15409 LY2109761 ≥98% 10mg $176 2024-03-01 Buy
Chemenu CM146238 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine 98% 50mg $493 2021-12-16 Buy
ChemScene CS-0571 LY2109761 99.95% 5mg $80 2021-12-16 Buy
ChemScene CS-0571 LY2109761 99.95% 10mg $140 2021-12-16 Buy
ChemScene CS-0571 LY2109761 99.95% 50mg $430 2021-12-16 Buy

Properties

Boiling point :640.9±55.0 °C(Predicted)
Density :1.34
storage temp. :Store at -20°C
solubility :≥22.1 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :6.27±0.10(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2.

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