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ChemicalBook >> CAS DataBase List >> KT5720

KT5720

KT5720 price.
  • $81 - $1400
  • Product name: KT5720
  • CAS: 108068-98-0
  • MF: C32H31N3O5
  • MW: 537.61
  • EINECS:810-587-2
  • MDL Number:MFCD09878277
  • Synonyms:(9R,10S,12S)-2,3,9,10,11,12-HEXAHYDRO-10-HYDROXY-9-METHYL-1-OXO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-10-CARBOXYLIC ACID, HEXYL ESTER;KT5720;PROTEIN KINASE INHIBITOR KT 5720;9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, (9R,10S,12S)-;(9s,10s,12r)-2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1h-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid hexyl ester;9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-I][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-hydroxy-9-methyl-1-oxo-, hexyl ester, (9R,10R,12S)-rel-;Aids004395;Aids-004395
21 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50ug
  • 50μg
  • 100μg
  • 100ug
  • 0.1mg
  • 250μg
  • 250ug
  • 500μg
  • 500ug
  • 1MG
  • 2.5mg
  • 5MG
  • 100U
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000144
  • Product descriptionKT 5720 95.00%
  • Packaging1MG
  • Price$672.09
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000144
  • Product descriptionKT 5720 95.00%
  • Packaging5MG
  • Price$1344.43
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9002
  • Product descriptionKT 5720
  • Packaging50ug
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9002
  • Product descriptionKT 5720
  • Packaging100ug
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9002
  • Product descriptionKT 5720
  • Packaging250ug
  • Price$431
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB9002
  • Product descriptionKT 5720
  • Packaging500ug
  • Price$764
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIK1003
  • Product descriptionKT 5720
  • Packaging100ug
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIK1003
  • Product descriptionKT 5720
  • Packaging1mg
  • Price$1356
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011011
  • Product descriptionKT 5720 ≥98%
  • Packaging50μg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011011
  • Product descriptionKT 5720 ≥98%
  • Packaging100μg
  • Price$129
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011011
  • Product descriptionKT 5720 ≥98%
  • Packaging250μg
  • Price$298
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011011
  • Product descriptionKT 5720 ≥98%
  • Packaging500μg
  • Price$435
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002494
  • Product descriptionKT 5720 ≥99.0%
  • Packaging50ug
  • Price$432
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002494
  • Product descriptionKT 5720 ≥99.0%
  • Packaging100ug
  • Price$740
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420320
  • Product descriptionKT5720 - CAS 108068-98-0 - Calbiochem A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (Ki = 56 nM) that is prepared by a chemical modification of K-252a.
  • Packaging50μG
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number420323
  • Product descriptionInSolution KT5720 - CAS 108068-98-0 - Calbiochem
  • Packaging50μg
  • Price$159
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0000144 KT 5720 95.00% 1MG $672.09 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000144 KT 5720 95.00% 5MG $1344.43 2021-12-16 Buy
ApexBio Technology B9002 KT 5720 50ug $96 2021-12-16 Buy
ApexBio Technology B9002 KT 5720 100ug $182 2021-12-16 Buy
ApexBio Technology B9002 KT 5720 250ug $431 2021-12-16 Buy
ApexBio Technology B9002 KT 5720 500ug $764 2021-12-16 Buy
Apolloscientific BIK1003 KT 5720 100ug $211 2021-12-16 Buy
Apolloscientific BIK1003 KT 5720 1mg $1356 2021-12-16 Buy
Cayman Chemical 10011011 KT 5720 ≥98% 50μg $81 2024-03-01 Buy
Cayman Chemical 10011011 KT 5720 ≥98% 100μg $129 2024-03-01 Buy
Cayman Chemical 10011011 KT 5720 ≥98% 250μg $298 2024-03-01 Buy
Cayman Chemical 10011011 KT 5720 ≥98% 500μg $435 2024-03-01 Buy
ChemScene CS-0002494 KT 5720 ≥99.0% 50ug $432 2021-12-16 Buy
ChemScene CS-0002494 KT 5720 ≥99.0% 100ug $740 2021-12-16 Buy
Sigma-Aldrich 420320 KT5720 - CAS 108068-98-0 - Calbiochem A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (Ki = 56 nM) that is prepared by a chemical modification of K-252a. 50μG $144 2024-03-01 Buy
Sigma-Aldrich 420323 InSolution KT5720 - CAS 108068-98-0 - Calbiochem 50μg $159 2024-03-01 Buy

Properties

Boiling point :715.0±60.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :methanol: 5 mg/mL
form :powder
pka :11.96±0.40(Predicted)
color :white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. KT 5720 is one of a family of compounds synthesized by the fungus Nocardiopsis sp. It blocks PKA signaling through competitive inhibition of ATP with a Ki value of 60 nM. Reported IC50 values vary widely depending upon ATP concentration tested and can range from 56 nM (low ATP) to 3 μM (physiologic ATP). Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBα, and GSK3β at concentrations as effective as or more potent than that for inhibition of PKA.