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ChemicalBook >> CAS DataBase List >> Isopropyl unoprostone

Isopropyl unoprostone

Isopropyl unoprostone price.
  • $57 - $1853
  • Product name: Isopropyl unoprostone
  • CAS: 120373-24-2
  • MF: C25H44O5
  • MW: 424.61
  • EINECS:1312995-182-4
  • MDL Number:MFCD00886951
  • Synonyms:RESCULA;UNOPROSTONE ISOPROPYL ESTER;isopropyl unoprostone;9ALPHA,11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID, ISOPROPYL ESTER;(5z)-7-((1r,2r,3r,5s)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl)-5-heptenoic acid 1-methylethyl ester;13,14-dihydro-15-keto-20-ethyl-pgf;13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA ISOPROPYL ESTER;(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-(3-oxodecyl)cyclopenthyl]-5-heptenoic Acid Isopropyl Ester
9 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1MG
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product numberN919
  • Product descriptionUnoprostoneisopropylester
  • Packaging5mg
  • Price$391
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberN919
  • Product descriptionUnoprostoneisopropylester
  • Packaging10mg
  • Price$618
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004053
  • Product descriptionISOPROPYL UNOPROSTONE 95.00%
  • Packaging1MG
  • Price$163.8
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16681
  • Product descriptionUnoprostone isopropyl ester ≥98%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16681
  • Product descriptionUnoprostone isopropyl ester ≥98%
  • Packaging5mg
  • Price$257
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16681
  • Product descriptionUnoprostone isopropyl ester ≥98%
  • Packaging10mg
  • Price$456
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16681
  • Product descriptionUnoprostone isopropyl ester ≥98%
  • Packaging50mg
  • Price$1853
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number18800
  • Product descriptionUnoprostone
  • Packaging5mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberU800050
  • Product descriptionUnoprostoneIsopropylEster
  • Packaging5mg
  • Price$880
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific N919 Unoprostoneisopropylester 5mg $391 2021-12-16 Buy
AK Scientific N919 Unoprostoneisopropylester 10mg $618 2021-12-16 Buy
American Custom Chemicals Corporation API0004053 ISOPROPYL UNOPROSTONE 95.00% 1MG $163.8 2021-12-16 Buy
Cayman Chemical 16681 Unoprostone isopropyl ester ≥98% 1mg $57 2024-03-01 Buy
Cayman Chemical 16681 Unoprostone isopropyl ester ≥98% 5mg $257 2024-03-01 Buy
Cayman Chemical 16681 Unoprostone isopropyl ester ≥98% 10mg $456 2024-03-01 Buy
Cayman Chemical 16681 Unoprostone isopropyl ester ≥98% 50mg $1853 2024-03-01 Buy
Medical Isotopes, Inc. 18800 Unoprostone 5mg $950 2021-12-16 Buy
TRC U800050 UnoprostoneIsopropylEster 5mg $880 2021-12-16 Buy

Properties

Boiling point :546.3±45.0 °C(Predicted)
Density :1.019±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Oil
pka :14.79±0.70(Predicted)
color :Clear Colourless
CAS DataBase Reference :120373-24-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Unoprostone isopropyl ester (Rescula) is the clinically approved, prodrug form of unoprostone, which is a free acid analog of prostaglandin F2α (PGF2α). Both latanoprost and Rescula have been approved for the treatment of ocular hypertension. Both analogs of PGF2α are believed to act by increasing the rate of aqueous humor outflow through the uveoscleral pathway. Both drugs are believed to act as prodrugs, with endogenous esterases within the eye releasing the free acid active form of the drug. The typical does of Rescula (one drop of 0.12% solution) is nearly 100 times that of latanoprost. Rescula has very little activity on isolated DP or TP receptors, less than 0.0005% the activity of PGE2 on EP3 receptors, and about 3% of the activity of PGF2α on FP receptors.

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