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ChemicalBook >> CAS DataBase List >> Isocyclosporin A

Isocyclosporin A

Isocyclosporin A price.
  • $121 - $1732.5
  • Product name: Isocyclosporin A
  • CAS: 59865-16-6
  • MF: C62H111N11O12
  • MW: 1202.61
  • EINECS:
  • MDL Number:MFCD11111450
  • Synonyms:30-ethyl-34-[(Z)-hex-4-en-2-yl]-4,7,10,12,15,19,25,28-octamethyl-33-me thylamino-6,9,18,24-tetrakis(2-methylpropyl)-3,21-dipropan-2-yl-1-oxa- 4,7,10,13,16,19,22,25,28,31-decazacyclotetratriacontane-2,5,8,11,14,17 ,20,23,26,29,32-undecone;isocyclosporin A;Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy*-N-methyl-5-[(E)-1-propenyl]-L-Leu-]];L-Valine, N-(3-hydroxy-4-methyl-2-(methylamino)-1-oxo-6-octenyl)-L-(alpha-aminobutyryl)-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-, theta1-1actone, (2S-(2R*,3S*,4S*,6E))-;(2S,3R,4R,6E)-3-Hydroxy-4-Methyl-2-(MethylaMino)-6-octenoyl-(2S)-2-aMinobutanoyl-N-Methylglycyl-N-Methyl-L-leucyl-L-valyl-N-Methyl-L-leucyl-L-alanyl-D-alanyl-N-Methyl-L-leucyl-N-Methyl-L-leucyl-N-Methyl-L-valine (111)-Lactone;[2S-(2R*,3S*,4S*,6E)]-N-[3-Hydroxy-4-methyl-2-(methylamino)-1-oxo-6-octenyl]-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine theta1-lactone;IsoCyclosporine;Cyclosporin Impurity 9
11 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • AvaChem
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50MG
  • ManufacturerAK Scientific
  • Product numberY0259
  • Product descriptionIsocyclosporinA
  • Packaging1mg
  • Price$233
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006762
  • Product descriptionISOCYCLOSPORIN A 95.00%
  • Packaging5MG
  • Price$756.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006762
  • Product descriptionISOCYCLOSPORIN A 95.00%
  • Packaging50MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2060
  • Product descriptionIsocyclosporin A
  • Packaging5mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2060
  • Product descriptionIsocyclosporin A
  • Packaging10mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2060
  • Product descriptionIsocyclosporin A
  • Packaging25mg
  • Price$665
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19462
  • Product descriptionIsocyclosporin A ≥98%
  • Packaging1mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19462
  • Product descriptionIsocyclosporin A ≥98%
  • Packaging5mg
  • Price$392
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberI811500
  • Product descriptionIsoCyclosporinA
  • Packaging25mg
  • Price$785
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberI811500
  • Product descriptionIsoCyclosporinA
  • Packaging50mg
  • Price$1390
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product numberI8856-01
  • Product descriptionIsocyclosporin A
  • Packaging1mg
  • Price$362
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0259 IsocyclosporinA 1mg $233 2021-12-16 Buy
American Custom Chemicals Corporation API0006762 ISOCYCLOSPORIN A 95.00% 5MG $756.25 2021-12-16 Buy
American Custom Chemicals Corporation API0006762 ISOCYCLOSPORIN A 95.00% 50MG $1732.5 2021-12-16 Buy
AvaChem 2060 Isocyclosporin A 5mg $145 2021-12-16 Buy
AvaChem 2060 Isocyclosporin A 10mg $275 2021-12-16 Buy
AvaChem 2060 Isocyclosporin A 25mg $665 2021-12-16 Buy
Cayman Chemical 19462 Isocyclosporin A ≥98% 1mg $121 2024-03-01 Buy
Cayman Chemical 19462 Isocyclosporin A ≥98% 5mg $392 2024-03-01 Buy
TRC I811500 IsoCyclosporinA 25mg $785 2021-12-16 Buy
TRC I811500 IsoCyclosporinA 50mg $1390 2021-12-16 Buy
Usbiological I8856-01 Isocyclosporin A 1mg $362 2021-12-16 Buy

Properties

Melting point :148-152°C
Boiling point :1280.5±65.0 °C(Predicted)
Density :1.13±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
pka :13.42±0.70(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic
InChIKey :QEKLELUAISGHEL-VWEOAMRINA-N

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
H362 May cause harm to breast-fed children Reproductive toxicity, effects on or via lactation Additional category P201, P260, P263, P264, P270,P308+P313
Precautionary statements:
P201 Obtain special instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy/while nursing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. This rearrangement has been used as the basis of a HPLC fluorescence for quantifying cyclosporin A. The pharmacology of isocyclosporin A has received little attention.

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