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ChemicalBook >> CAS DataBase List >> Indibulin

Indibulin

Indibulin price.
  • $177 - $1741
  • Product name: Indibulin
  • CAS: 204205-90-3
  • MF: C22H16ClN3O2
  • MW: 389.83
  • EINECS:
  • MDL Number:MFCD05861105
  • Synonyms:Nascapine;ZIO 301;2-(1-(4-Chlorophenylmethyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide;Indibulin;2-[1-(4-Chlorobenzyl)-1H-indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide;lindiblin;2-[1-[(4-chlorophenyl)methyl]indol-3-yl]-2-oxo-N-pyridin-4-ylacetamide;1H-Indole-3-acetamide, 1-[(4-chlorophenyl)methyl]-α-oxo-N-4-pyridinyl-
12 prices
Selected condition：
Brand
  • Alichem
  • American Custom Chemicals Corporation
  • Chemenu
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 10MG
  • 25mg
  • 50MG
  • 100mg
  • 10
  • 0.5G
  • 1g
  • ManufacturerAlichem
  • Product number204205903
  • Product description2-(1-(4-Chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide
  • Packaging1g
  • Price$1464.32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002198
  • Product descriptionD-24851 95.00%
  • Packaging10MG
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002198
  • Product descriptionD-24851 95.00%
  • Packaging50MG
  • Price$725
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002198
  • Product descriptionD-24851 95.00%
  • Packaging0.5G
  • Price$1016
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM148012
  • Product description2-(1-(4-chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 95%
  • Packaging1g
  • Price$1641
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007536
  • Product descriptionIndibulin 99.61%
  • Packaging50mg
  • Price$580
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0007536
  • Product descriptionIndibulin 99.61%
  • Packaging100mg
  • Price$1020
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11168730
  • Product description2-(1-(4-Chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 95+%
  • Packaging1g
  • Price$1741
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3728
  • Product descriptionIndibulin ≥98%(HPLC)
  • Packaging10
  • Price$177
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3728
  • Product descriptionIndibulin ≥98%(HPLC)
  • Packaging50
  • Price$735
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberI533753
  • Product descriptionIndibulin
  • Packaging25mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255508
  • Product descriptionIndibulin
  • Packaging10mg
  • Price$423
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 204205903 2-(1-(4-Chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 1g $1464.32 2021-12-16 Buy
American Custom Chemicals Corporation API0002198 D-24851 95.00% 10MG $495 2021-12-16 Buy
American Custom Chemicals Corporation API0002198 D-24851 95.00% 50MG $725 2021-12-16 Buy
American Custom Chemicals Corporation API0002198 D-24851 95.00% 0.5G $1016 2021-12-16 Buy
Chemenu CM148012 2-(1-(4-chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 95% 1g $1641 2021-12-16 Buy
ChemScene CS-0007536 Indibulin 99.61% 50mg $580 2021-12-16 Buy
ChemScene CS-0007536 Indibulin 99.61% 100mg $1020 2021-12-16 Buy
Crysdot CD11168730 2-(1-(4-Chlorobenzyl)-1H-indol-3-yl)-2-oxo-N-(pyridin-4-yl)acetamide 95+% 1g $1741 2021-12-16 Buy
Tocris 3728 Indibulin ≥98%(HPLC) 10 $177 2021-12-16 Buy
Tocris 3728 Indibulin ≥98%(HPLC) 50 $735 2021-12-16 Buy
TRC I533753 Indibulin 25mg $195 2021-12-16 Buy
Usbiological 255508 Indibulin 10mg $423 2021-12-16 Buy

Properties

Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:33.25(Max Conc. mg/mL);85.29(Max Conc. mM)
form :A solid
pka :9.38±0.70(Predicted)
color :Off-white to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Indibulin (D-24851; ZIO-301), a novel synthetic small molecule microtubule inhibitor, destabilizes microtubules and has antitumor activity but does not exhibit neurotoxicity in preclinical animal studies. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis. The drug can discriminate between highly posttranslationally modified tubulin present in mature neuronal microtubules, and less-modified tubulin present in immature neuronal or nonneuronal microtubules.

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