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ChemicalBook >> CAS DataBase List >> Ilomastat

Ilomastat

Ilomastat price.
  • $32 - $5661
  • Product name: Ilomastat
  • CAS: 142880-36-2
  • MF: C20H28N4O4
  • MW: 388.46
  • EINECS:
  • MDL Number:MFCD00917040
  • Synonyms:(2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-butanediamide Ilomastat (GM6001, Galardin);Galardin CS 610;Ilomastat, >=98%;(r)-n4-hydroxy-n1-[(s)-2-(1h-indol-3-yl)-1-methylcarbamoly-ethyl]-2-isobutyl-succinamide;galardin tm;(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide;Galardin, GM6001, Ilomastat;SANTACRUZ
39 prices
Selected condition:
Brand
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Ark Pharm
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerAlfa Aesar
  • Product numberJ65687
  • Product descriptionGM 6001
  • Packaging1mg
  • Price$81.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65687
  • Product descriptionGM 6001
  • Packaging5mg
  • Price$366
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging2mg
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging5mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging10mg
  • Price$122
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging50mg
  • Price$407
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging100mg
  • Price$666
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA237914
  • Product descriptionGM 6001 98%
  • Packaging1g
  • Price$5661
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4050
  • Product descriptionGM 6001
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS488887
  • Product descriptionGM 6001 ≥98%
  • Packaging2mg
  • Price$56
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS488887
  • Product descriptionGM 6001 ≥98%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS488887
  • Product descriptionGM 6001 ≥98%
  • Packaging10mg
  • Price$121
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS488887
  • Product descriptionGM 6001 ≥98%
  • Packaging50mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS488887
  • Product descriptionGM 6001 ≥98%
  • Packaging100mg
  • Price$659
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberAK468728
  • Product descriptionGM 6001 98%
  • Packaging2mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberAK468728
  • Product descriptionGM 6001 98%
  • Packaging10mg
  • Price$244
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J65687 GM 6001 1mg $81.1 2021-12-16 Buy
Alfa Aesar J65687 GM 6001 5mg $366 2023-06-20 Buy
Ambeed A237914 GM 6001 98% 2mg $57 2021-12-16 Buy
Ambeed A237914 GM 6001 98% 5mg $74 2021-12-16 Buy
Ambeed A237914 GM 6001 98% 10mg $122 2021-12-16 Buy
Ambeed A237914 GM 6001 98% 50mg $407 2021-12-16 Buy
Ambeed A237914 GM 6001 98% 100mg $666 2021-12-16 Buy
Ambeed A237914 GM 6001 98% 1g $5661 2021-12-16 Buy
ApexBio Technology A4050 GM 6001 5mg $100 2021-12-16 Buy
Arctom AS488887 GM 6001 ≥98% 2mg $56 2021-12-16 Buy
Arctom AS488887 GM 6001 ≥98% 5mg $73 2021-12-16 Buy
Arctom AS488887 GM 6001 ≥98% 10mg $121 2021-12-16 Buy
Arctom AS488887 GM 6001 ≥98% 50mg $403 2021-12-16 Buy
Arctom AS488887 GM 6001 ≥98% 100mg $659 2021-12-16 Buy
Ark Pharm AK468728 GM 6001 98% 2mg $110 2021-12-16 Buy
Ark Pharm AK468728 GM 6001 98% 10mg $244 2021-12-16 Buy

Properties

Density :1.228±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in DMSO, and 100% ethanol.
pka :9.16±0.20(Predicted)
form :Off-white solid
color :White
Sensitive :Moisture Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :NITYDPDXAAFEIT-DYVFJYSZSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). It inhibits zinc-containing thermolysin and elastase from P. aeruginosa, both with Ki values of 20 nM. GM 6001 inhibits MMP-1, -2, -7, -8, -9, -12, -13, -14, -16, and -26 with Ki or IC50 values between 0.1 and 10 nM. It inhibits disintegrin and metalloproteinase domain-containing (ADAM) proteins ADAM9, ADAM10, ADAM12, and ADAM17 at nanomolar concentrations. It less potently inhibits lethal factor from B. anthracis anthrax lethal toxin (Ki = 2.74 μM). GM 6001 also impairs the growth of the human pathogen Chlamydia by inhibiting peptide deformylase, which contains iron rather than zinc (IC50 = 38 nM).

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