IPI 145
- $68 - $2550
- Product name: IPI 145
- CAS: 1201438-56-3
- MF: C22H17ClN6O
- MW: 416.86
- EINECS:200-256-5
- MDL Number:MFCD15144635
- Synonyms:IPI-145;IPI-145 (INK-1197);IPI-145 INK197;8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone;IPI-145, >=98%;Duvelisib (IPI-145, INK1197);DUVELISIB (IPI-145);1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-
29 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 20mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M005
- Product descriptionIPI-145 ≥95%
- Packaging5mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1175-M050
- Product descriptionIPI-145 ≥95%
- Packaging50mg
- Price$1004
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1175
- Product descriptionIPI145
- Packaging100mg
- Price$1660
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60268
- Product descriptionDuvelisib(IPI-145)
- Packaging20mg
- Price$258
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146252
- Product descriptionDuvelisib (IPI-145, INK1197) >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146252
- Product descriptionDuvelisib (IPI-145, INK1197) >98%
- Packaging250mg
- Price$1060.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146252
- Product descriptionDuvelisib (IPI-145, INK1197) >98%
- Packaging1g
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP43074
- Product descriptionIPI 145
- Packaging10mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFP43074
- Product descriptionIPI 145
- Packaging50mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16800
- Product descriptionIPI-145 ≥98%
- Packaging500μg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16800
- Product descriptionIPI-145 ≥98%
- Packaging1mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16800
- Product descriptionIPI-145 ≥98%
- Packaging5mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16800
- Product descriptionIPI-145 ≥98%
- Packaging10mg
- Price$335
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM138713
- Product description(S)-3-(1-(9H-Purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one 98%
- Packaging100mg
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0888
- Product descriptionDuvelisib 99.91%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0888
- Product descriptionDuvelisib 99.91%
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | SYN-1175-M005 | IPI-145 ≥95% | 5mg | $178 | 2021-12-16 | Buy |
Adipogen Life Sciences | SYN-1175-M050 | IPI-145 ≥95% | 50mg | $1004 | 2021-12-16 | Buy |
AK Scientific | SYN1175 | IPI145 | 100mg | $1660 | 2021-12-16 | Buy |
Arctom | CFN60268 | Duvelisib(IPI-145) | 20mg | $258 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146252 | Duvelisib (IPI-145, INK1197) >98% | 100mg | $615.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146252 | Duvelisib (IPI-145, INK1197) >98% | 250mg | $1060.8 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146252 | Duvelisib (IPI-145, INK1197) >98% | 1g | $2245.7 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP43074 | IPI 145 | 10mg | $125 | 2021-12-16 | Buy |
Biosynth Carbosynth | FP43074 | IPI 145 | 50mg | $225 | 2021-12-16 | Buy |
Cayman Chemical | 16800 | IPI-145 ≥98% | 500μg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 16800 | IPI-145 ≥98% | 1mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 16800 | IPI-145 ≥98% | 5mg | $201 | 2024-03-01 | Buy |
Cayman Chemical | 16800 | IPI-145 ≥98% | 10mg | $335 | 2024-03-01 | Buy |
Chemenu | CM138713 | (S)-3-(1-(9H-Purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one 98% | 100mg | $299 | 2021-12-16 | Buy |
ChemScene | CS-0888 | Duvelisib 99.91% | 5mg | $70 | 2021-12-16 | Buy |
ChemScene | CS-0888 | Duvelisib 99.91% | 10mg | $100 | 2021-12-16 | Buy |
Properties
Melting point :205-206o C
Boiling point :757.8±60.0 °C(Predicted)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White solid.
pka :10.05±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :757.8±60.0 °C(Predicted)
Density :1.474±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
form :White solid.
pka :10.05±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kγ and PI3Kδ (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kγ and PI3Kδ are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus animal models. It also has potential applications in immunotherapy and in certain cancers.More related product prices
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