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ChemicalBook >> CAS DataBase List >> HELENALIN

HELENALIN

HELENALIN price.
  • $160 - $660
  • Product name: HELENALIN
  • CAS: 6754-13-8
  • MF: C15H18O4
  • MW: 262.3
  • EINECS:
  • MDL Number:MFCD01674580
  • Synonyms:(3as-(3aalpha,4alpha,4abeta,7aalpha,8alpha,9aalpha))-ethyl-3-methylene ;HELENALIN(SH);HELENALIN;6alpha,8beta-dihydroxy-4-oxoambrosa-2,11(13)-dien-12-oicacid12,8-lactone ;a-dimethyl-3-methyleneazuleno[6,5-b]-furan-2,5-dione ;ambrosa-2,11(13)-dien-12-oicacid,6-alpha,8-beta-dihydroxy-4-oxo-,12,8-lacton ;ambrosa-2,11(13)-dien-12-oicacid,6alpha,8beta-dihydroxy-4-oxo-,12,8-lactone ;azuleno(6,5-b)furan-2,5-dione,3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dim
7 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
Package
  • 0.25mg
  • 500μG
  • 500ug
  • 1mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0435-M001
  • Product descriptionHelenalin ≥96%(HPLC)
  • Packaging1mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2004CA
  • Product descriptionHelenalin
  • Packaging1mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17050
  • Product descriptionHelenalin ≥98%
  • Packaging1mg
  • Price$504
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0078850
  • Product descriptionHelenalin 98.29%
  • Packaging500ug
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0078850
  • Product descriptionHelenalin 98.29%
  • Packaging1mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number374000
  • Product descriptionHelenalin, A. chamissonis ssp. foliosa
  • Packaging500μG
  • Price$617
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH230000
  • Product descriptionHelenalin
  • Packaging0.25mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0435-M001 Helenalin ≥96%(HPLC) 1mg $390 2021-12-16 Buy
AK Scientific 2004CA Helenalin 1mg $660 2021-12-16 Buy
Cayman Chemical 17050 Helenalin ≥98% 1mg $504 2024-03-01 Buy
ChemScene CS-0078850 Helenalin 98.29% 500ug $270 2021-12-16 Buy
ChemScene CS-0078850 Helenalin 98.29% 1mg $410 2021-12-16 Buy
Sigma-Aldrich 374000 Helenalin, A. chamissonis ssp. foliosa 500μG $617 2024-03-01 Buy
TRC H230000 Helenalin 0.25mg $160 2021-12-16 Buy

Properties

Melting point :167-168°
alpha :D25 -102.8° (c = 3.64 in 95% ethanol)
Boiling point :325.55°C (rough estimate)
Density :1.0772 (rough estimate)
refractive index :1.4300 (estimate)
storage temp. :-20°
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml).
form :White to off-white solid.
pka :13.29±0.60(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
LogP :0.870

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-κB at doses from 1 to 20 μM. Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it alkylates these groups on the p65 subunit of NF-κB. It also suppresses the proliferation of cancer cells through multiple mechanisms, including the prevention of signaling through NF-κB. Helenalin has antibacterial and anti-protozoal activities.

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