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ChemicalBook >> CAS DataBase List >> Galeterone

Galeterone

Galeterone price.
  • $25 - $2650
  • Product name: Galeterone
  • CAS: 851983-85-2
  • MF: C26H32N2O
  • MW: 388.55
  • EINECS:806-537-4
  • MDL Number:MFCD16660907
  • Synonyms:NX41765;(3S,8R,9S,10R,13S,14S)-17-(1H-Benzo[d]imidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;(3beta)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol;Galeterone;VN 124;TOK-001 (Galeterone);Galeterone,TOK-001;(3S,10R,13S)-17-(1H-benzo[d]imidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
25 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 10
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • 50mg
  • 50
  • 100mg
  • 200mg
  • 500mg
  • ManufacturerAK Scientific
  • Product numberY0281
  • Product descriptionGaleterone
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013705
  • Product descriptionGALETERONE 95.00%
  • Packaging5MG
  • Price$327.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8623
  • Product descriptionTOK-001
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT65187
  • Product descriptionGaleterone
  • Packaging10mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT65187
  • Product descriptionGaleterone
  • Packaging50mg
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17586
  • Product descriptionGaleterone ≥98%
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17586
  • Product descriptionGaleterone ≥98%
  • Packaging5mg
  • Price$88
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17586
  • Product descriptionGaleterone ≥98%
  • Packaging10mg
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17586
  • Product descriptionGaleterone ≥98%
  • Packaging25mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM161791
  • Product description(3S,8R,9S,10R,13S,14S)-17-(1H-benzo[d]imidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 98%
  • Packaging100mg
  • Price$589
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging50mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging200mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0334
  • Product descriptionGaleterone 99.90%
  • Packaging500mg
  • Price$1150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0281 Galeterone 100mg $550 2021-12-16 Buy
American Custom Chemicals Corporation API0013705 GALETERONE 95.00% 5MG $327.8 2021-12-16 Buy
ApexBio Technology A8623 TOK-001 10mg $160 2021-12-16 Buy
Biosynth Carbosynth FT65187 Galeterone 10mg $95 2021-12-16 Buy
Biosynth Carbosynth FT65187 Galeterone 50mg $333 2021-12-16 Buy
Cayman Chemical 17586 Galeterone ≥98% 1mg $25 2024-03-01 Buy
Cayman Chemical 17586 Galeterone ≥98% 5mg $88 2024-03-01 Buy
Cayman Chemical 17586 Galeterone ≥98% 10mg $138 2024-03-01 Buy
Cayman Chemical 17586 Galeterone ≥98% 25mg $216 2024-03-01 Buy
Chemenu CM161791 (3S,8R,9S,10R,13S,14S)-17-(1H-benzo[d]imidazol-1-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 98% 100mg $589 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 5mg $60 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 10mg $90 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 50mg $270 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 100mg $450 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 200mg $650 2021-12-16 Buy
ChemScene CS-0334 Galeterone 99.90% 500mg $1150 2021-12-16 Buy

Properties

Melting point :189-190℃
Boiling point :564.5±60.0 °C(Predicted)
Density :1.28
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Ethyl Aceatae (Slightly, Heated)
pka :14.71±0.70(Predicted)
form :Solid
color :White to Off-White
InChIKey :PAFKTGFSEFKSQG-MRFMOSGMNA-N
SMILES :C1C[C@]2(C)C3CC[C@]4(C)C([n]5cnc6ccccc56)=CCC4C3CC=C2C[C@H]1O |&1:2,7,27,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P281 Use personal protective equipment as required.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The cytochrome P450 (CYP) isoform CYP17 is also known as steroid 17α-hydroxylase/17,20 lyase because it catalyzes both 17α-hydroxylase and 17,20 lyase reactions in the synthesis of steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids. Galeterone is a CYP17 inhibitor (IC50 = 300 nM) that has been shown to competitively block synthetic androgen binding (EC50 = 845 nM) and to antagonize the androgen receptor in transcriptional activation assays. Galeterone can inhibit the growth of castration-resistant prostate cancer cells with an IC50 value of 2.9 μM and demonstrates synergy with everolimus or gefitinib for growth inhibition.

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