GSK 2330672
- $110 - $3900
- Product name: GSK 2330672
- CAS: 1345982-69-5
- MF: C28H38N2O7S
- MW: 546.68
- EINECS:604-604-1
- MDL Number:MFCD28386358
- Synonyms:GSK 2330672;GSK 2330672; GSK-2330672;3-[[(3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxo-5-phenyl-4,5-dihydro-2H-1λ6,4-benzothiazepin-8-yl]methylamino]pentanedioic acid;Pentanedioic acid, 3-((((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4-benzothiazepin-8-yl)methyl)amino)-;CS-2639;Iinerixibat;Iinerixibat (GSK2330672);linerixibat
10 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- Crysdot
- DC Chemicals
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4578DL
- Product descriptionLinerixibat
- Packaging5mg
- Price$671
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23843
- Product descriptionGSK2330672 ≥98%
- Packaging1mg
- Price$110
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23843
- Product descriptionGSK2330672 ≥98%
- Packaging5mg
- Price$515
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23843
- Product descriptionGSK2330672 ≥98%
- Packaging10mg
- Price$918
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31003808
- Product descriptionGSK2330672 98+%
- Packaging5mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003808
- Product descriptionGSK2330672 98+%
- Packaging10mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003808
- Product descriptionGSK2330672 98+%
- Packaging50mg
- Price$1042
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31003808
- Product descriptionGSK2330672 98+%
- Packaging100mg
- Price$1459
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9712
- Product descriptionIinerixibat >98%
- Packaging250mg
- Price$1900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9712
- Product descriptionIinerixibat >98%
- Packaging1g
- Price$3900
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4578DL | Linerixibat | 5mg | $671 | 2021-12-16 | Buy |
Cayman Chemical | 23843 | GSK2330672 ≥98% | 1mg | $110 | 2024-03-01 | Buy |
Cayman Chemical | 23843 | GSK2330672 ≥98% | 5mg | $515 | 2024-03-01 | Buy |
Cayman Chemical | 23843 | GSK2330672 ≥98% | 10mg | $918 | 2024-03-01 | Buy |
Crysdot | CD31003808 | GSK2330672 98+% | 5mg | $208 | 2021-12-16 | Buy |
Crysdot | CD31003808 | GSK2330672 98+% | 10mg | $347 | 2021-12-16 | Buy |
Crysdot | CD31003808 | GSK2330672 98+% | 50mg | $1042 | 2021-12-16 | Buy |
Crysdot | CD31003808 | GSK2330672 98+% | 100mg | $1459 | 2021-12-16 | Buy |
DC Chemicals | DC9712 | Iinerixibat >98% | 250mg | $1900 | 2021-12-16 | Buy |
DC Chemicals | DC9712 | Iinerixibat >98% | 1g | $3900 | 2021-12-16 | Buy |
Properties
Boiling point :730.8±60.0 °C(Predicted)
Density :1.218±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form :A crystalline solid
pka :3.27±0.10(Predicted)
color :White to off-white
Density :1.218±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form :A crystalline solid
pka :3.27±0.10(Predicted)
color :White to off-white
Safety Information
Symbol(GHS): | ||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
GSK2330672 is an inhibitor of the apical sodium-dependent bile acid transporter (ASBT; IC50s = 42, 2.1, and 1.9 nM for human, mouse, and rat ASBT, respectively). In vivo, GSK2330672 (0.05 mg/kg) stimulates fecal bile acid secretion, reduces hemoglobin A1c (HbA1c) and plasma glucose levels, and increases total GLP-1 and plasma insulin in Zucker diabetic fatty (ZDF) rats.Related product price
- GSK2879552
$32-1000 - GSK2636771
$44-2245.7 - GSK 2801
$32-1677