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ChemicalBook >> CAS DataBase List >> FILIPIN III

FILIPIN III

FILIPIN III price.
  • $110 - $1062
  • Product name: FILIPIN III
  • CAS: 480-49-9
  • MF: C35H58O11
  • MW: 654.83
  • EINECS:
  • MDL Number:MFCD30742956
  • Synonyms:filimarisin ;28-dimethyl--3-(1-hydroxyhexyl)-1 ;1',26-Dihydroxyfilipin I;15-Deoxylagosin;1'-epi-Filipin IV;1'-Hydroxyfilipin II;FILIPIN III;filipin iii from streptomyces*filipinensis
14 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 1
  • 500μg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1769AH
  • Product descriptionFilipinIII
  • Packaging5mg
  • Price$657
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1769AH
  • Product descriptionFilipinIII
  • Packaging10mg
  • Price$1062
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPRB0000101
  • Product description14-DEOXYLAGOSIN 95.00%
  • Packaging5MG
  • Price$498.04
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIA4324
  • Product descriptionFilipinIII
  • Packaging5mg
  • Price$588
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70440
  • Product descriptionFilipin III ≥90%
  • Packaging500μg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70440
  • Product descriptionFilipin III ≥90%
  • Packaging1mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70440
  • Product descriptionFilipin III ≥90%
  • Packaging5mg
  • Price$602
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0099763
  • Product descriptionFilipinIII 99.00%
  • Packaging1mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF4767
  • Product descriptionFilipin III from Streptomyces filipinensis ≥85% (HPLC)
  • Packaging1mg
  • Price$198
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF4767
  • Product descriptionFilipin III from Streptomyces filipinensis ≥85% (HPLC)
  • Packaging5mg
  • Price$785
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number6250
  • Product descriptionFilipinIII ≥98%(HPLC)
  • Packaging1
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberF337003
  • Product descriptionFilipinIII
  • Packaging1mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number450066
  • Product descriptionFilipin III
  • Packaging1mg
  • Price$509
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number366882
  • Product descriptionFilipin III
  • Packaging1mg
  • Price$352
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1769AH FilipinIII 5mg $657 2021-12-16 Buy
AK Scientific 1769AH FilipinIII 10mg $1062 2021-12-16 Buy
American Custom Chemicals Corporation PRB0000101 14-DEOXYLAGOSIN 95.00% 5MG $498.04 2021-12-16 Buy
Apolloscientific BIA4324 FilipinIII 5mg $588 2021-12-16 Buy
Cayman Chemical 70440 Filipin III ≥90% 500μg $110 2024-03-01 Buy
Cayman Chemical 70440 Filipin III ≥90% 1mg $152 2024-03-01 Buy
Cayman Chemical 70440 Filipin III ≥90% 5mg $602 2024-03-01 Buy
ChemScene CS-0099763 FilipinIII 99.00% 1mg $650 2021-12-16 Buy
Sigma-Aldrich F4767 Filipin III from Streptomyces filipinensis ≥85% (HPLC) 1mg $198 2024-03-01 Buy
Sigma-Aldrich F4767 Filipin III from Streptomyces filipinensis ≥85% (HPLC) 5mg $785 2024-03-01 Buy
Tocris 6250 FilipinIII ≥98%(HPLC) 1 $195 2021-12-16 Buy
TRC F337003 FilipinIII 1mg $180 2021-12-16 Buy
Usbiological 450066 Filipin III 1mg $509 2021-12-16 Buy
Usbiological 366882 Filipin III 1mg $352 2021-12-16 Buy

Properties

Melting point :163-180° (Bergy, Eble)
alpha :D25 -245° (c = 0.8 in DMF)
Boiling point :913.9±65.0 °C(Predicted)
Density :1.161±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :Soluble in Methanol (up to 10 mg/ml)
form :solid
pka :12.77±0.70(Predicted)
color :White or light yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in methanol may be stored under inert gas at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cholesterol is both an important structural component of cell membranes and an early intermediate in hormone and bile acid biosynthesis. The localization and measurement of cholesterol in cells is therefore of great interest. Filipin is the collective name given to four isomeric polyene macrolides isolated from cultures of S. filipinensis; Filipin III is the predominant isomer and the one used in most studies. Filipin binds to cholesterol in membranes, forming ultrastructural aggregates and complexes which can be visualized by freeze-fracture electron microscopy. The binding of cholesterol also decreases the intrinsic fluorescence of Filipin, and this property has also been used to detect cholesterol in membrane fractions.

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