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ChemicalBook >> CAS DataBase List >> Edoxaban-d6

Edoxaban-d6

Edoxaban-d6 price.
  • $396 - $1850
  • Product name: Edoxaban-d6
  • CAS: 1304701-57-2
  • MF: C24H30ClN7O4S
  • MW: 548.06
  • EINECS:
  • MDL Number:MFCD32661438
  • Synonyms:Edoxaban-d6;N-[(1S,2R,4S)-4-[bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide;[2H6]-Edoxaban;Edoxaban hydrochloride salt;2H6]-Edoxaban hydrochloride salt
6 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 500ug
  • 500μg
  • 1mg
  • 5mg
  • Manufactureraablocks
  • Product numberAA01E0QG
  • Product descriptionEdoxaban-d6 ≥99%deuteratedforms(d1-d6)
  • Packaging1mg
  • Price$782
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4287DK
  • Product descriptionN-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide
  • Packaging1mg
  • Price$889
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25760
  • Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
  • Packaging500μg
  • Price$396
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25760
  • Product descriptionEdoxaban-d6 ≥99% deuterated forms (d1-d6)
  • Packaging1mg
  • Price$711
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberE555522
  • Product descriptionEdoxaban-d6
  • Packaging5mg
  • Price$1850
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number448076
  • Product descriptionEdoxaban-d6
  • Packaging500ug
  • Price$531
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01E0QG Edoxaban-d6 ≥99%deuteratedforms(d1-d6) 1mg $782 2021-12-16 Buy
AK Scientific 4287DK N-[(1S,2R,4S)-4-[Bis(trideuteriomethyl)carbamoyl]-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide 1mg $889 2021-12-16 Buy
Cayman Chemical 25760 Edoxaban-d6 ≥99% deuterated forms (d1-d6) 500μg $396 2024-03-01 Buy
Cayman Chemical 25760 Edoxaban-d6 ≥99% deuterated forms (d1-d6) 1mg $711 2024-03-01 Buy
TRC E555522 Edoxaban-d6 5mg $1850 2021-12-16 Buy
Usbiological 448076 Edoxaban-d6 500ug $531 2021-12-16 Buy

Properties

Melting point :>205°C (dec.)
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Chloroform (Slightly), Dichloromethane (Slightly)
form :Solid
color :Pale Orange to Pale Red
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Edoxaban-d6 is intended for use as an internal standard for the quantification of edoxaban by GC- or LC-MS. Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated partial thromboplastin, and thrombin clotting times in a concentration-dependent manner ex vivo in human plasma. Oral administration of edoxaban (0.5-12.5 mg/kg) reduces thrombus formation and prolongs prothrombin time in a dose-dependent manner in rat and rabbit models of venous stasis thrombosis. It also reduces thrombus formation in a rat model of platinum wire-induced venous thrombosis. Formulations containing edoxaban have been used to prevent stroke in patients with atrial fibrillation.