ESI 09
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- $32 - $1300
- Product name: ESI 09
- CAS: 263707-16-0
- MF: C16H15ClN4O2
- MW: 330.77
- EINECS:
- MDL Number:MFCD00109218
- Synonyms:ESI 09;ESI09;ESI-09;(E)-3-(5-tert-butylisoxazol-3-yl)-2-(2-(3-chlorophenyl)hydrazono)-3-oxopropanenitrile;α-[2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-b-oxo-3-isoxazolepropanenitrile;alpha-[(3-Chlorophenyl)hydrazono]-5-(1,1-dimethylethyl)-beta-oxo-3-isoxazolepropanenitrile;α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile;3-Isoxazolepropanenitrile, α-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-
22 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5MG
- 10
- 1mg
- 10mg
- 50
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberY1877
- Product descriptionESI-09
- Packaging100mg
- Price$955
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0002134
- Product description3-[5-(TERTBUTYL)ISOXAZOL-3-YL]-2-[2-(3-CHLOROPHENYL)HYDRAZONO]-3-OXOPROPANENITRILE 95.00%
- Packaging5MG
- Price$499.39
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4814
- Product descriptionESI-09
- Packaging100mg
- Price$474
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19130
- Product descriptionESI-09 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19130
- Product descriptionESI-09 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19130
- Product descriptionESI-09 ≥95%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19130
- Product descriptionESI-09 ≥95%
- Packaging25mg
- Price$305
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3420
- Product descriptionESI-09 98.75%
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3420
- Product descriptionESI-09 98.75%
- Packaging10mg
- Price$105
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3420
- Product descriptionESI-09 98.75%
- Packaging50mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3420
- Product descriptionESI-09 98.75%
- Packaging100mg
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002470
- Product descriptionESI-09 98+%
- Packaging10mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8443
- Product descriptionESI-09 >98%
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8443
- Product descriptionESI-09 >98%
- Packaging250mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8443
- Product descriptionESI-09 >98%
- Packaging1g
- Price$1300
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0814
- Product descriptionESI-09 ≥98% (HPLC)
- Packaging5mg
- Price$152
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1877 | ESI-09 | 100mg | $955 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0002134 | 3-[5-(TERTBUTYL)ISOXAZOL-3-YL]-2-[2-(3-CHLOROPHENYL)HYDRAZONO]-3-OXOPROPANENITRILE 95.00% | 5MG | $499.39 | 2021-12-16 | Buy |
| ApexBio Technology | B4814 | ESI-09 | 100mg | $474 | 2021-12-16 | Buy |
| Cayman Chemical | 19130 | ESI-09 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19130 | ESI-09 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 19130 | ESI-09 ≥95% | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 19130 | ESI-09 ≥95% | 25mg | $305 | 2024-03-01 | Buy |
| ChemScene | CS-3420 | ESI-09 98.75% | 5mg | $65 | 2021-12-16 | Buy |
| ChemScene | CS-3420 | ESI-09 98.75% | 10mg | $105 | 2021-12-16 | Buy |
| ChemScene | CS-3420 | ESI-09 98.75% | 50mg | $390 | 2021-12-16 | Buy |
| ChemScene | CS-3420 | ESI-09 98.75% | 100mg | $590 | 2021-12-16 | Buy |
| Crysdot | CD31002470 | ESI-09 98+% | 10mg | $158 | 2021-12-16 | Buy |
| DC Chemicals | DC8443 | ESI-09 >98% | 100mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC8443 | ESI-09 >98% | 250mg | $650 | 2021-12-16 | Buy |
| DC Chemicals | DC8443 | ESI-09 >98% | 1g | $1300 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0814 | ESI-09 ≥98% (HPLC) | 5mg | $152 | 2024-03-01 | Buy |
Properties
Melting point :>175°C (dec.)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :, faint yellow to dark orange
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
form :powder
color :, faint yellow to dark orange
Safety Information
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Description
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). ESI-09 is an inhibitor of Epac1 and Epac2 with IC50 values of 3.2 and 1.4 μM, respectively. It shows no activity against PKA at concentrations as high as 25 μM. ESI-09 has been shown to block Akt phosphorylation and insulin secretion in pancreatic β cells, as well as to block the migration of AsPC-1 and PANC-1 pancreatic cancer cells in vitro.Related product price
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