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ChemicalBook >> CAS DataBase List >> Dexamethasone palmitate

Dexamethasone palmitate

Dexamethasone palmitate price.
  • $50 - $1732.5
  • Product name: Dexamethasone palmitate
  • CAS: 14899-36-6
  • MF: C38H59FO6
  • MW: 630.87
  • EINECS:
  • MDL Number:
  • Synonyms:(11β,16α)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-[(1-oxohexadecyl)oxy]pregna-1,4-diene-3,20-dione;DEXAMETHASOME PALMITATE;Palmitic acid, 21-ester with 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (8CI);Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-[(1-oxohexadecyl)oxy]-, (11β,16α)-;Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-palmitate (6CI, 8CI);9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 21-palmitate;Dexamethasone palmitate;21-(Palmitoyloxy)-9α-fluoro-11β,17α-dihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione
12 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • ChemScene
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 250mg
  • 500mg
  • 1G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0012845
  • Product descriptionDEXAMETHASONE PALMITATE 95.00%
  • Packaging100MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0012845
  • Product descriptionDEXAMETHASONE PALMITATE 95.00%
  • Packaging1G
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21400
  • Product descriptionDexamethasone 21-palmitate
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21400
  • Product descriptionDexamethasone 21-palmitate
  • Packaging50mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21400
  • Product descriptionDexamethasone 21-palmitate
  • Packaging100mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21400
  • Product descriptionDexamethasone 21-palmitate
  • Packaging250mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD21400
  • Product descriptionDexamethasone 21-palmitate
  • Packaging500mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102469
  • Product descriptionDexamethasonepalmitate >98.0%
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102469
  • Product descriptionDexamethasonepalmitate >98.0%
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102469
  • Product descriptionDexamethasonepalmitate >98.0%
  • Packaging50mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0102469
  • Product descriptionDexamethasonepalmitate >98.0%
  • Packaging100mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD298830
  • Product descriptionDexamethasone21-Palmitate
  • Packaging250mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0012845 DEXAMETHASONE PALMITATE 95.00% 100MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0012845 DEXAMETHASONE PALMITATE 95.00% 1G $1732.5 2021-12-16 Buy
Biosynth Carbosynth FD21400 Dexamethasone 21-palmitate 25mg $160 2021-12-16 Buy
Biosynth Carbosynth FD21400 Dexamethasone 21-palmitate 50mg $220 2021-12-16 Buy
Biosynth Carbosynth FD21400 Dexamethasone 21-palmitate 100mg $300 2021-12-16 Buy
Biosynth Carbosynth FD21400 Dexamethasone 21-palmitate 250mg $700 2021-12-16 Buy
Biosynth Carbosynth FD21400 Dexamethasone 21-palmitate 500mg $1200 2021-12-16 Buy
ChemScene CS-0102469 Dexamethasonepalmitate >98.0% 5mg $50 2021-12-16 Buy
ChemScene CS-0102469 Dexamethasonepalmitate >98.0% 10mg $80 2021-12-16 Buy
ChemScene CS-0102469 Dexamethasonepalmitate >98.0% 50mg $170 2021-12-16 Buy
ChemScene CS-0102469 Dexamethasonepalmitate >98.0% 100mg $290 2021-12-16 Buy
TRC D298830 Dexamethasone21-Palmitate 250mg $480 2021-12-16 Buy

Properties

Melting point :60-65 °C
Boiling point :710.1±60.0 °C(Predicted)
Density :1.12
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka :11.99±0.70(Predicted)
form :Solid
color :White to Pale Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).

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