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ChemicalBook >> CAS DataBase List >> Darunavir

Darunavir

Darunavir price.
  • $5 - $2400
  • Product name: Darunavir
  • CAS: 206361-99-1
  • MF: C27H37N3O7S
  • MW: 547.66
  • EINECS:606-590-1
  • MDL Number:MFCD09260006
  • Synonyms:[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester;Darunavir;TMC-114;UIC-94017;[(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-β]-furan-3-yl Ester;D03656;Darunavir (usan/inn);(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
59 prices
Selected condition：
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Ark Pharm
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 1mg
  • 5mg
  • 1unit
  • 10mM(in 1mL DMSO)
  • 10mg
  • 50
  • 25mg
  • 50mg
  • 10
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3712-M050
  • Product descriptionDarunavir ≥98%(HPLC)
  • Packaging50mg
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5831
  • Product descriptionDarunavir
  • Packaging5g
  • Price$1508
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX5831
  • Product descriptionDarunavir
  • Packaging10g
  • Price$1994
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging5mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging100mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging250mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA116353
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+%
  • Packaging1g
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8206
  • Product descriptionDarunavir
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8206
  • Product descriptionDarunavir
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8206
  • Product descriptionDarunavir
  • Packaging10mM(in 1mL DMSO)
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8206
  • Product descriptionDarunavir
  • Packaging50mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014355
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014355
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98%
  • Packaging5mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS014355
  • Product description(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98%
  • Packaging10mg
  • Price$9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-3712-M050 Darunavir ≥98%(HPLC) 50mg $210 2021-12-16 Buy
AK Scientific X5831 Darunavir 5g $1508 2021-12-16 Buy
AK Scientific X5831 Darunavir 10g $1994 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 1mg $5 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 5mg $7 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 10mg $9 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 100mg $17 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 250mg $25 2021-12-16 Buy
Ambeed A116353 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate 98+% 1g $65 2021-12-16 Buy
ApexBio Technology A8206 Darunavir 1unit $28 2021-12-16 Buy
ApexBio Technology A8206 Darunavir 5mg $60 2021-12-16 Buy
ApexBio Technology A8206 Darunavir 10mM(in 1mL DMSO) $140 2021-12-16 Buy
ApexBio Technology A8206 Darunavir 50mg $330 2021-12-16 Buy
Arctom AS014355 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98% 1mg $5 2021-12-16 Buy
Arctom AS014355 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98% 5mg $7 2021-12-16 Buy
Arctom AS014355 (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate ≥98% 10mg $9 2021-12-16 Buy

Properties

Melting point :74-760C
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
pka :11.43±0.46(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Darunavir is a second generation protease inhibitor that targets the HIV-1 protease. It demonstrates extremely potent activity against the infectivity and replication of various strains of HIV-1, including several that are resistant to first generation protease inhibitors (IC50s = 3-30 nM). Darunavir has been reported to inhibit both cell-free diffusion and cell-to-cell spread of HIV-1 with IC50 values of 2.5 and 2.8 nM, respectively.