Cucurbitacin E
- $35 - $1540
- Product name: Cucurbitacin E
- CAS: 18444-66-1
- MF: C32H44O8
- MW: 556.69
- EINECS:242-325-2
- MDL Number:MFCD00135936
- Synonyms:A-ELATERIN;ALPHA-ELATERIN;CUCURBITACIN E;CUCURBITACIN E(SH);19-nor-9-beta,10-alpha-lanosta-1,5,23-triene-3,11,22-trione,2,16-alpha,20,25-t ;25-acetate ;alpha-elaterine ;cucurbitacine-e
36 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0474-M001
- Product descriptionCucurbitacin E ≥98%(HPLC)
- Packaging1mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0474-M025
- Product descriptionCucurbitacin E ≥98%(HPLC)
- Packaging25mg
- Price$560
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0059
- Product descriptionCucurbitacin E
- Packaging10mg
- Price$434
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0059
- Product descriptionCucurbitacin E
- Packaging1mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA513376
- Product descriptionCucurbitacin E 98+%
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA513376
- Product descriptionCucurbitacin E 98+%
- Packaging50mg
- Price$481
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA513376
- Product descriptionCucurbitacin E 98+%
- Packaging25mg
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA513376
- Product descriptionCucurbitacin E 98+%
- Packaging10mg
- Price$195
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA513376
- Product descriptionCucurbitacin E 98+%
- Packaging5mg
- Price$118
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007173
- Product descriptionCUCURBITACIN E 95.00%
- Packaging10MG
- Price$967.77
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2791
- Product descriptionCucurbitacin E
- Packaging20mg
- Price$365
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN90154
- Product descriptionCucurbitacin E ≥98%
- Packaging10mg
- Price$368
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY073793
- Product descriptionCucurbitacinE,98%,fromCucumismeloL.
- Packaging10mg
- Price$490.91
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2360
- Product descriptionCucurbitacin E
- Packaging5mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2360
- Product descriptionCucurbitacin E
- Packaging10mg
- Price$159
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2360
- Product descriptionCucurbitacin E
- Packaging25mg
- Price$309
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | AG-CN2-0474-M001 | Cucurbitacin E ≥98%(HPLC) | 1mg | $35 | 2021-12-16 | Buy |
Adipogen Life Sciences | AG-CN2-0474-M025 | Cucurbitacin E ≥98%(HPLC) | 25mg | $560 | 2021-12-16 | Buy |
AK Scientific | Y0059 | Cucurbitacin E | 10mg | $434 | 2021-12-16 | Buy |
AK Scientific | Y0059 | Cucurbitacin E | 1mg | $144 | 2021-12-16 | Buy |
Ambeed | A513376 | Cucurbitacin E 98+% | 100mg | $700 | 2021-12-16 | Buy |
Ambeed | A513376 | Cucurbitacin E 98+% | 50mg | $481 | 2021-12-16 | Buy |
Ambeed | A513376 | Cucurbitacin E 98+% | 25mg | $310 | 2021-12-16 | Buy |
Ambeed | A513376 | Cucurbitacin E 98+% | 10mg | $195 | 2021-12-16 | Buy |
Ambeed | A513376 | Cucurbitacin E 98+% | 5mg | $118 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | SHG0007173 | CUCURBITACIN E 95.00% | 10MG | $967.77 | 2021-12-16 | Buy |
ApexBio Technology | N2791 | Cucurbitacin E | 20mg | $365 | 2021-12-16 | Buy |
Arctom | CFN90154 | Cucurbitacin E ≥98% | 10mg | $368 | 2021-12-16 | Buy |
Arctom | SY073793 | CucurbitacinE,98%,fromCucumismeloL. | 10mg | $490.91 | 2021-12-16 | Buy |
AvaChem | 2360 | Cucurbitacin E | 5mg | $89 | 2021-12-16 | Buy |
AvaChem | 2360 | Cucurbitacin E | 10mg | $159 | 2021-12-16 | Buy |
AvaChem | 2360 | Cucurbitacin E | 25mg | $309 | 2021-12-16 | Buy |
Properties
Melting point :228-234°C
alpha :D -59° (c = 0.7 in chloroform)
Boiling point :545.56°C (rough estimate)
Density :1.1059 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :8.51±0.70(Predicted)
color :white to beige
optical activity :[α]/D -60 to -75°, c = 0.7 (CDCl3)
InChIKey :NDYMQXYDSVBNLL-MUYMLXPFSA-N
LogP :3.150 (est)
alpha :D -59° (c = 0.7 in chloroform)
Boiling point :545.56°C (rough estimate)
Density :1.1059 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :8.51±0.70(Predicted)
color :white to beige
optical activity :[α]/D -60 to -75°, c = 0.7 (CDCl3)
InChIKey :NDYMQXYDSVBNLL-MUYMLXPFSA-N
LogP :3.150 (est)
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Cucurbitacin E is a plant-derived triterpene that has diverse biological activities. At a concentration of 10 pM, it reduces MPP+-induced death of neuronal PC12 cells through inhibition of autophagy in vitro. Cucurbitacin E inhibits growth of T24 bladder, MDA-MB-468 and MCF-7 breast, PC3 prostate, and colorectal cancer cell lines (IC50s = 50-1,000 nM) through induction of G2/M arrest and apoptosis. It increases bilirubin binding to human serum albumin (HSA) in human plasma in a dose-dependent manner. Cucurbitacin E also inhibits depolymerization of actin filaments isolated from rabbit skeletal muscle actin and in HeLa cells.Related product price
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$37-1339.8 - CUCURBITACIN D
$85-1428.28 - 1,2-Cyclohexanedione
$6-1000
Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Greenpure Biopharma CO.,Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Jusheng Technology Co.,Ltd.
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Wuhan ChemNorm Biotech Co.,Ltd.