Clotrimazole
- $10 - $927
- Product name: Clotrimazole
- CAS: 23593-75-1
- MF: C22H17ClN2
- MW: 344.84
- EINECS:245-764-8
- MDL Number:MFCD00057220
- Synonyms:component of Otomax;Empecid;FB 5097;fb5097 ;Gyne lotrimin;Imidazole, 1-(o-chloro-alpha,alpha-diphenylbenzyl)-;Methane, bis-phenyl-(2-chlorophenyl)-1-imidazolyl-;Mono-baycuten
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Brand
- AHH
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10ug
- 50mg
- 100ug
- 50
- 100mg
- 200mg
- 500mg
- 1g
- 5g
- 25g
- 100G
- 250g
- y0000849
- c2430000
- ManufacturerAHH
- Product numberMT-49455
- Product descriptionClotrimazole 98%
- Packaging250g
- Price$440
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ99593
- Product descriptionClotrimazole
- Packaging1g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberN713
- Product descriptionClotrimazole
- Packaging5g
- Price$34
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63895
- Product descriptionClotrimazole
- Packaging5g
- Price$66.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63895
- Product descriptionClotrimazole
- Packaging25g
- Price$232.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002086
- Product descriptionCLOTRIMAZOLE 95.00%
- Packaging1G
- Price$123.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8401
- Product descriptionClotrimazole
- Packaging1g
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3163
- Product descriptionClotrimazole-BAYb5097 98%
- Packaging50mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15278
- Product descriptionClotrimazole ≥98%
- Packaging50mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15278
- Product descriptionClotrimazole ≥98%
- Packaging100mg
- Price$41
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15278
- Product descriptionClotrimazole ≥98%
- Packaging1g
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerChem-Impex
- Product number01311
- Product descriptionClotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay)
- Packaging1G
- Price$17.47
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number01311
- Product descriptionClotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay)
- Packaging5G
- Price$29.12
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number01311
- Product descriptionClotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay)
- Packaging25G
- Price$93.18
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number01311
- Product descriptionClotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay)
- Packaging100G
- Price$343.62
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number01311
- Product descriptionClotrimazole,99%(Assay) 99%(Assay)
- Packaging250G
- Price$666.4
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-49455 | Clotrimazole 98% | 250g | $440 | 2021-12-16 | Buy |
AK Scientific | J99593 | Clotrimazole | 1g | $10 | 2021-12-16 | Buy |
AK Scientific | N713 | Clotrimazole | 5g | $34 | 2021-12-16 | Buy |
Alfa Aesar | J63895 | Clotrimazole | 5g | $66.65 | 2024-03-01 | Buy |
Alfa Aesar | J63895 | Clotrimazole | 25g | $232.65 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | API0002086 | CLOTRIMAZOLE 95.00% | 1G | $123.9 | 2021-12-16 | Buy |
ApexBio Technology | A8401 | Clotrimazole | 1g | $70 | 2021-12-16 | Buy |
Axon Medchem | Axon3163 | Clotrimazole-BAYb5097 98% | 50mg | $55 | 2021-12-16 | Buy |
Cayman Chemical | 15278 | Clotrimazole ≥98% | 50mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 15278 | Clotrimazole ≥98% | 100mg | $41 | 2024-03-01 | Buy |
Cayman Chemical | 15278 | Clotrimazole ≥98% | 1g | $57 | 2024-03-01 | Buy |
Chem-Impex | 01311 | Clotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay) | 1G | $17.47 | 2021-12-16 | Buy |
Chem-Impex | 01311 | Clotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay) | 5G | $29.12 | 2021-12-16 | Buy |
Chem-Impex | 01311 | Clotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay) | 25G | $93.18 | 2021-12-16 | Buy |
Chem-Impex | 01311 | Clotrimazole,≥99%(Assay)Antibiotic ≥99%(Assay) | 100G | $343.62 | 2021-12-16 | Buy |
Chem-Impex | 01311 | Clotrimazole,99%(Assay) 99%(Assay) | 250G | $666.4 | 2021-12-16 | Buy |
Properties
Melting point :147-149°C
Boiling point :501.14°C (rough estimate)
Density :1.1095 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :2-8°C
solubility :Soluble in chloroform, DMSO, DMF and alcohols
pka :pKa 4.7(EtOH 50%aq ) (Uncertain)
form :Solid
color :White to Almost white
Water Solubility :<10mg/L(25 ºC)
λmax :556nm(Phosphate buffer sol.)(lit.)
Merck :14,2417
InChI :InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChIKey :VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES :C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1
NIST Chemistry Reference :Clotrimazole(23593-75-1)
Boiling point :501.14°C (rough estimate)
Density :1.1095 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :2-8°C
solubility :Soluble in chloroform, DMSO, DMF and alcohols
pka :pKa 4.7(EtOH 50%aq ) (Uncertain)
form :Solid
color :White to Almost white
Water Solubility :<10mg/L(25 ºC)
λmax :556nm(Phosphate buffer sol.)(lit.)
Merck :14,2417
InChI :InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
InChIKey :VNFPBHJOKIVQEB-UHFFFAOYSA-N
SMILES :C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1
NIST Chemistry Reference :Clotrimazole(23593-75-1)
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Clotrimazole is an imidazole antifungal that is active against a wide variety of fungal forms and is effective in many types of fungal infections. It tightly binds sterol 14-α demethylase isoform B from A. fumigatus (KD = 103 nM) and, like other imidazoles, disturbs the fungal cell membrane. In mammalian cells, clotrimazole potently inhibits the calcium-dependent potassium channels Kv1.3 and IK-1 (IC50 = 6.0 and 0.07 μM, respectively).More related product prices
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