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ChemicalBook >> CAS DataBase List >> Clofibrate

Clofibrate

Clofibrate price.
  • $14 - $2000
  • Product name: Clofibrate
  • CAS: 637-07-0
  • MF: C12H15ClO3
  • MW: 242.7
  • EINECS:211-277-4
  • MDL Number:MFCD00000615
  • Synonyms:Androtor;2-(4-Chlorophenoxy)isobutyric Acid Ethyl Ester Ethyl 2-(4-Chlorophenoxy)isobutyrate;2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester, Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, Ethyl 2-(4-chlorophenoxy)isobutyrate;2-(P-chlorophenoxy)-2-methylpropionic*acid ethyl;Phenoxyisobutyricacidethylester;Fibrate;Clofibrate 0.1;Anti-PPFIA1 (N-terminal) antibody produced in rabbit
36 prices
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  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Heterocyclics
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 5MG
  • 100mg
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  • 500mg
  • 1g
  • 5g
  • 25g
  • 10g
  • c2300000
  • 50g
  • 100g
  • 250g
  • 500G
  • ManufacturerAK Scientific
  • Product numberK009
  • Product descriptionClofibrate
  • Packaging1g
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60342
  • Product descriptionClofibrate, 95+%
  • Packaging1g
  • Price$21.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60342
  • Product descriptionClofibrate, 95+%
  • Packaging5g
  • Price$24.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60342
  • Product descriptionClofibrate, 95+%
  • Packaging25g
  • Price$89.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ60342
  • Product descriptionClofibrate, 95+%
  • Packaging100g
  • Price$249.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0026101
  • Product descriptionATROMID 95.00%
  • Packaging5MG
  • Price$496.39
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3610
  • Product descriptionClofibrate
  • Packaging10g
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20499
  • Product descriptionClofibrate
  • Packaging10g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20499
  • Product descriptionClofibrate
  • Packaging25g
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20499
  • Product descriptionClofibrate
  • Packaging50g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20499
  • Product descriptionClofibrate
  • Packaging100g
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20499
  • Product descriptionClofibrate
  • Packaging250g
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10956
  • Product descriptionClofibrate ≥98%
  • Packaging500mg
  • Price$18
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10956
  • Product descriptionClofibrate ≥98%
  • Packaging1g
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10956
  • Product descriptionClofibrate ≥98%
  • Packaging5g
  • Price$129
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10956
  • Product descriptionClofibrate ≥98%
  • Packaging10g
  • Price$223
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific K009 Clofibrate 1g $14 2021-12-16 Buy
Alfa Aesar J60342 Clofibrate, 95+% 1g $21.65 2024-03-01 Buy
Alfa Aesar J60342 Clofibrate, 95+% 5g $24.65 2024-03-01 Buy
Alfa Aesar J60342 Clofibrate, 95+% 25g $89.65 2024-03-01 Buy
Alfa Aesar J60342 Clofibrate, 95+% 100g $249.65 2024-03-01 Buy
American Custom Chemicals Corporation API0026101 ATROMID 95.00% 5MG $496.39 2021-12-16 Buy
ApexBio Technology B3610 Clofibrate 10g $120 2021-12-16 Buy
Biosynth Carbosynth FC20499 Clofibrate 10g $50 2021-12-16 Buy
Biosynth Carbosynth FC20499 Clofibrate 25g $100 2021-12-16 Buy
Biosynth Carbosynth FC20499 Clofibrate 50g $180 2021-12-16 Buy
Biosynth Carbosynth FC20499 Clofibrate 100g $320 2021-12-16 Buy
Biosynth Carbosynth FC20499 Clofibrate 250g $550 2021-12-16 Buy
Cayman Chemical 10956 Clofibrate ≥98% 500mg $18 2024-03-01 Buy
Cayman Chemical 10956 Clofibrate ≥98% 1g $32 2024-03-01 Buy
Cayman Chemical 10956 Clofibrate ≥98% 5g $129 2024-03-01 Buy
Cayman Chemical 10956 Clofibrate ≥98% 10g $223 2024-03-01 Buy

Properties

Melting point :<25 °C
Boiling point :154 °C
Density :1.14 g/mL at 25 °C(lit.)
refractive index :n20/D 1.503
Flash point :113 °C
storage temp. :2-8°C
solubility :Soluble to 100 mM in DMSO.
form :liquid
color :clear, colorless
Water Solubility :97.08mg/L(room temperature)
Merck :14,2377
BRN :1913459
CAS DataBase Reference :637-07-0(CAS DataBase Reference)
IARC :3 (Vol. Sup 7, 66) 1996
NIST Chemistry Reference :Clofibrate(637-07-0)
EPA Substance Registry System :Clofibrate (637-07-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor involved in the regulation of lipid homeostasis. Activation of PPARα results in expression of a variety of genes, particularly those involved in fatty acid β-oxidation, binding, and transport. Clofibrate is a PPARα agonist and a member of a class of hypolipidemic drugs that includes fenofibrate and benzafibrate, which have been used clinically to treat dyslipidemia and cardiovascular disease. In a transactivation assay, clofibrate exhibits EC50 values of 50 and 55 μM for mouse and human PPARα, respectively. It also binds to PPARγ, but with 10-fold less affinity and is inactive at PPARδ at concentrations up to 100 μM.

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