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ChemicalBook >> CAS DataBase List >> Chloral hydrate

Chloral hydrate

Chloral hydrate price.
  • $34 - $4307.11
  • Product name: Chloral hydrate
  • CAS: 302-17-0
  • MF: C2H3Cl3O2
  • MW: 165.4
  • EINECS:206-117-5
  • MDL Number:MFCD00044479
  • Synonyms:chloralex ;chloralihydras ;chloralvan ;Cohidrate;Dormal;Escre;Ethanediol,2,2,2-trichloro- ;Felsules
14 prices
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Brand
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5MG
  • 100g
  • 250g
  • 500G
  • 1kg
  • 2Kg
  • 5kg
  • 10Kg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006338
  • Product descriptionCHLORAL HYDRATE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0006338
  • Product descriptionCHLORAL HYDRATE 95.00%
  • Packaging500G
  • Price$4307.11
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC45435
  • Product descriptionChloral hydrate
  • Packaging500g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC45435
  • Product descriptionChloral hydrate
  • Packaging1kg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC45435
  • Product descriptionChloral hydrate
  • Packaging2Kg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC45435
  • Product descriptionChloral hydrate
  • Packaging5kg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC45435
  • Product descriptionChloral hydrate
  • Packaging10Kg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21843
  • Product descriptionChloral hydrate ≥95%
  • Packaging1mg
  • Price$34
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21843
  • Product descriptionChloral hydrate ≥95%
  • Packaging5mg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC8383
  • Product descriptionChloral hydrate ≥98% (titration)
  • Packaging1kg
  • Price$363
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product numberC8383
  • Product descriptionChloral hydrate ≥98% (titration)
  • Packaging250g
  • Price$119
  • Updated2024-03-01
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  • ManufacturerSigma-Aldrich
  • Product numberC8383
  • Product descriptionChloral hydrate ≥98% (titration)
  • Packaging100g
  • Price$72.8
  • Updated2024-03-01
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  • ManufacturerTRC
  • Product numberT774055
  • Product descriptionTrichloroacetaldehydeHydrate
  • Packaging500g
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number291757
  • Product descriptionTrichloro
  • Packaging100g
  • Price$337
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0006338 CHLORAL HYDRATE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation API0006338 CHLORAL HYDRATE 95.00% 500G $4307.11 2021-12-16 Buy
Biosynth Carbosynth FC45435 Chloral hydrate 500g $55 2021-12-16 Buy
Biosynth Carbosynth FC45435 Chloral hydrate 1kg $100 2021-12-16 Buy
Biosynth Carbosynth FC45435 Chloral hydrate 2Kg $180 2021-12-16 Buy
Biosynth Carbosynth FC45435 Chloral hydrate 5kg $400 2021-12-16 Buy
Biosynth Carbosynth FC45435 Chloral hydrate 10Kg $650 2021-12-16 Buy
Cayman Chemical 21843 Chloral hydrate ≥95% 1mg $34 2024-03-01 Buy
Cayman Chemical 21843 Chloral hydrate ≥95% 5mg $85 2024-03-01 Buy
Sigma-Aldrich C8383 Chloral hydrate ≥98% (titration) 1kg $363 2024-03-01 Buy
Sigma-Aldrich C8383 Chloral hydrate ≥98% (titration) 250g $119 2024-03-01 Buy
Sigma-Aldrich C8383 Chloral hydrate ≥98% (titration) 100g $72.8 2024-03-01 Buy
TRC T774055 TrichloroacetaldehydeHydrate 500g $420 2021-12-16 Buy
Usbiological 291757 Trichloro 100g $337 2021-12-16 Buy

Properties

Melting point :57 °C(lit.)
Boiling point :97 °C
Density :1.43 g/mL at 20 °C
vapor pressure :19.998hPa at 25℃
refractive index :1.4603 (estimate)
Flash point :16 °C
storage temp. :0-6°C
solubility :Very soluble in water, freely soluble in ethanol (96 per cent).
pka :10(at 25℃)
form :A crystalline solid
Specific Gravity :1.91
PH :3.5-5.5 (20℃, 10%)
Water Solubility :660 g/100 mL
Merck :13,2080
BRN :1698497
Dielectric constant :5.5(15℃)
Stability :Stable, but may be air or light sensitive. Incompatible with alcohols, cyanides, iodine, strong bases, carbonates.
InChIKey :RNFNDJAIBTYOQL-UHFFFAOYSA-N
LogP :1.092 at 25℃
CAS DataBase Reference :302-17-0(CAS DataBase Reference)
IARC :2A (Vol. 63, 84, 106) 2014
NIST Chemistry Reference :Chloral hydrate(302-17-0)
EPA Substance Registry System :Chloral hydrate (302-17-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.

Description

Chloral hydrate is one of the oldest sedatives used for dental sedation. It was first synthesized in 1832 by Justus von Liebig and was the first synthetic central nervous system (CNS) depressant. It was used to treat delirium tremens, insomnia, and anxiety, although it is considered an unapproved drug by the US Food and Drug Administration. Initially considered to be a safer alternative to opium, it was noted to produce rapid unconsciousness when combined with ethanol. Physical dependence can occur with chronic use.
Chloral hydrate is classified as a sedative-hypnotic and is known to induce sleep in children. It has been very popular in pediatric dentistry since the mid-1950s. Chloral hydrate is rapidly absorbed following oral administration and is converted through its first pass in the liver to trichloroethanol,its active form. Trichloroethanol is conjugated in the liver and excreted in the urine. Like other agents that are metabolized in the liver, chloral hydrate may interact with other drugs, herbs, or foods resulting in clinically significant alterations of the agents (e.g.,warfarin).

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