Brinzolamide-d5
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- $279 - $2783
- Product name: Brinzolamide-d5
- CAS: 1217651-02-9
- MF: C12H21N3O5S3
- MW: 383.5
- EINECS:
- MDL Number:
- Synonyms:[2H5]-Brinzolamide;Brinzolamide-d5;(R)-4-((ethyl-d5)amino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
6 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- TRC
Package
- 500μg
- 0.5MG
- 1mg
- 5MG
- ManufacturerAK Scientific
- Product number7669DG
- Product descriptionBrinzolamide-d5
- Packaging1mg
- Price$646
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006690
- Product descriptionBRINZOLAMIDE-D5 95.00%
- Packaging0.5MG
- Price$797.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006690
- Product descriptionBRINZOLAMIDE-D5 95.00%
- Packaging5MG
- Price$2783
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30006
- Product descriptionBrinzolamide-d5
- Packaging500μg
- Price$279
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30006
- Product descriptionBrinzolamide-d5
- Packaging1mg
- Price$501
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberB677602
- Product descriptionBrinzolamide-d5
- Packaging5mg
- Price$1980
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7669DG | Brinzolamide-d5 | 1mg | $646 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006690 | BRINZOLAMIDE-D5 95.00% | 0.5MG | $797.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006690 | BRINZOLAMIDE-D5 95.00% | 5MG | $2783 | 2021-12-16 | Buy |
| Cayman Chemical | 30006 | Brinzolamide-d5 | 500μg | $279 | 2024-03-01 | Buy |
| Cayman Chemical | 30006 | Brinzolamide-d5 | 1mg | $501 | 2024-03-01 | Buy |
| TRC | B677602 | Brinzolamide-d5 | 5mg | $1980 | 2021-12-16 | Buy |
Properties
storage temp. :Refrigerator
solubility :Ethanol
form :Solid
color :Crystalline
solubility :Ethanol
form :Solid
color :Crystalline
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | |||||||
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Description
Brinzolamide-d5 is intended for use as an internal standard for the quantification of brinzolamide by GC- or LC-MS. Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure in a rabbit model of spontaneous ocular hypertension. It also reduces intraocular pressure in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.Related product price
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