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ChemicalBook >> CAS DataBase List >> Bardoxolone

Bardoxolone

Bardoxolone price.
  • $10 - $2200
  • Product name: Bardoxolone
  • CAS: 218600-44-3
  • MF: C31H41NO4
  • MW: 491.66
  • EINECS:
  • MDL Number:MFCD07772296
  • Synonyms:2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid;CDDO(Bardoxolone);BARDOXOLONE;CDDO;RTA 401;Oleana-1,9(11)-dien-28-oic acid, 2-cyano-3,12-dioxo-;Bardoxolone;CDDO;RTA 401;2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid
35 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 0.5MG
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3470AH
  • Product descriptionBardoxolone
  • Packaging50mg
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging1mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging5mg
  • Price$22
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging10mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging100mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging250mg
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA165469
  • Product descriptionBardoxolone 98+%
  • Packaging1g
  • Price$535
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0007315
  • Product descriptionBARDOXOLONE 95.00%
  • Packaging0.5MG
  • Price$687.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0007315
  • Product descriptionBARDOXOLONE 95.00%
  • Packaging1MG
  • Price$837.38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0007315
  • Product descriptionBARDOXOLONE 95.00%
  • Packaging5MG
  • Price$1089
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3220
  • Product descriptionBardoxolone
  • Packaging50mg
  • Price$164
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3220
  • Product descriptionBardoxolone
  • Packaging500mg
  • Price$657
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS459585
  • Product descriptionBardoxolone ≥98%
  • Packaging100mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB30002
  • Product descriptionBardoxolone
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB30002
  • Product descriptionBardoxolone
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB30002
  • Product descriptionBardoxolone
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3470AH Bardoxolone 50mg $401 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 1mg $10 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 5mg $22 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 10mg $32 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 100mg $120 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 250mg $206 2021-12-16 Buy
Ambeed A165469 Bardoxolone 98+% 1g $535 2021-12-16 Buy
American Custom Chemicals Corporation SHG0007315 BARDOXOLONE 95.00% 0.5MG $687.5 2021-12-16 Buy
American Custom Chemicals Corporation SHG0007315 BARDOXOLONE 95.00% 1MG $837.38 2021-12-16 Buy
American Custom Chemicals Corporation SHG0007315 BARDOXOLONE 95.00% 5MG $1089 2021-12-16 Buy
ApexBio Technology A3220 Bardoxolone 50mg $164 2021-12-16 Buy
ApexBio Technology A3220 Bardoxolone 500mg $657 2021-12-16 Buy
Arctom AS459585 Bardoxolone ≥98% 100mg $325 2021-12-16 Buy
Biosynth Carbosynth FB30002 Bardoxolone 5mg $50 2021-12-16 Buy
Biosynth Carbosynth FB30002 Bardoxolone 10mg $80 2021-12-16 Buy
Biosynth Carbosynth FB30002 Bardoxolone 25mg $160 2021-12-16 Buy

Properties

Melting point :180-182 °C
Boiling point :632.9±55.0 °C(Predicted)
Density :1.18
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥49.2 mg/mL in DMSO; insoluble in H2O; ≥2.682 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
pka :4.52±0.70(Predicted)
color :White to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By suppressing reactive oxygen and nitrogen species (ROS/RNS) formation, it promotes the cellular control of ROS/RNS levels that would lead to DNA damage associated with tumorigenesis. In various cancer cell lines, CDDO has been shown to specifically inhibit proliferation and induce apoptosis. Mechanism studies revealed that CDDO is a ligand for peroxisome proliferator-activated receptor γ, and also that it induces genes regulated by Nrf2, including heme oxygenase-1 and eotaxin-1, which play a role in antioxidant response element signaling activity.

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