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ChemicalBook >> CAS DataBase List >> Avasimibe

Avasimibe

Avasimibe price.
  • $49 - $2250
  • Product name: Avasimibe
  • CAS: 166518-60-1
  • MF: C29H43NO4S
  • MW: 501.72
  • EINECS:1592732-453-0
  • MDL Number:MFCD00934956
  • Synonyms:Avasimibe, >=98%;2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate;[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;PD 148515;avasimibe;n-(2,6-dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide;N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE;((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER
36 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 25
  • 200mg
  • 250mg
  • 500MG
  • 5
  • 1g
  • ManufacturerAK Scientific
  • Product numberV2056
  • Product descriptionavasimibe
  • Packaging50mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging5mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging10mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging50mg
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging100mg
  • Price$418
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging250mg
  • Price$626
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156472
  • Product descriptionAvasimibe 95+%
  • Packaging1g
  • Price$2128
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000864
  • Product descriptionAVASIMIBE 95.00%
  • Packaging5MG
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000864
  • Product descriptionAVASIMIBE 95.00%
  • Packaging250MG
  • Price$862.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000864
  • Product descriptionAVASIMIBE 95.00%
  • Packaging500MG
  • Price$1325
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000864
  • Product descriptionAVASIMIBE 95.00%
  • Packaging1G
  • Price$2250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4318
  • Product descriptionAvasimibe
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0114
  • Product descriptionAvasimibe
  • Packaging5mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0114
  • Product descriptionAvasimibe
  • Packaging10mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0114
  • Product descriptionAvasimibe
  • Packaging50mg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60441
  • Product descriptionAvasimibe ≥98%
  • Packaging10mg
  • Price$118
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific V2056 avasimibe 50mg $240 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 5mg $147 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 10mg $191 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 50mg $322 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 100mg $418 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 250mg $626 2021-12-16 Buy
Ambeed A156472 Avasimibe 95+% 1g $2128 2021-12-16 Buy
American Custom Chemicals Corporation INB0000864 AVASIMIBE 95.00% 5MG $450 2021-12-16 Buy
American Custom Chemicals Corporation INB0000864 AVASIMIBE 95.00% 250MG $862.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0000864 AVASIMIBE 95.00% 500MG $1325 2021-12-16 Buy
American Custom Chemicals Corporation INB0000864 AVASIMIBE 95.00% 1G $2250 2021-12-16 Buy
ApexBio Technology A4318 Avasimibe 10mg $50 2021-12-16 Buy
Apolloscientific BISN0114 Avasimibe 5mg $109 2021-12-16 Buy
Apolloscientific BISN0114 Avasimibe 10mg $138 2021-12-16 Buy
Apolloscientific BISN0114 Avasimibe 50mg $334 2021-12-16 Buy
Arctom CFN60441 Avasimibe ≥98% 10mg $118 2021-12-16 Buy

Properties

Melting point :178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Acyl-Coenzyme A:cholesterol acyltransferases (ACAT1 and ACAT2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. Avasimibe is an orally bioavailable inhibitor of ACAT (IC50s = 24 and 9.2 μM for ACAT1 and ACAT2, respectively). It reduces foam cell formation in human macrophages in vitro, enhancing free cholesterol efflux and inhibiting the uptake of modified LDL and dose-dependently reduces plasma total triglyceride and VLDL cholesterol levels in cholesterol-fed animal models. Avasimibe inhibition of ACAT has been used to decrease amyloid β generation in models of Alzheimer’s disease.

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