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ChemicalBook >> CAS DataBase List >> Aminoquinol

Aminoquinol

Aminoquinol price.
  • $30 - $560
  • Product name: Aminoquinol
  • CAS: 10023-54-8
  • MF: C26H31Cl2N3
  • MW: 456.45
  • EINECS:
  • MDL Number:MFCD01709344
  • Synonyms:Aminoquinol;7-Chloro-2-(o-chlorostyryl)-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quin olin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diami;N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-dia;N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediamine tris(phosphate);1,4-Pentanediamine, N4-[7-chloro-2-[2-(2-chlorophenyl)ethenyl]-4-quinolinyl]-N1,N1-diethyl-;Aminoquinol DISCONTINUED. Please see C609759.
4 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Aronis compounds
  • Matrix Scientific
Package
  • 5MG
  • 20mg
  • 1g
  • ManufacturerAK Scientific
  • Product number7133AC
  • Product descriptionN4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine
  • Packaging1g
  • Price$560
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025379
  • Product descriptionAMINOQUINOL 95.00%
  • Packaging5MG
  • Price$501.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAronis compounds
  • Product numbere00599
  • Product descriptionN4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate)
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number009881
  • Product descriptionN-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate
  • Packaging1g
  • Price$378
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7133AC N4-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N1,N1-diethyl-pentane-1,4-diamine 1g $560 2021-12-16 Buy
American Custom Chemicals Corporation API0025379 AMINOQUINOL 95.00% 5MG $501.2 2021-12-16 Buy
Aronis compounds e00599 N4-{7-chloro-2-[2-(2-chlorophenyl)vinyl]-4-quinolinyl}-N1,N1-diethyl-1,4-pentanediaminetris(phosphate) 20mg $30 2021-12-16 Buy
Matrix Scientific 009881 N-*4*-{7-Chloro-2-[2-(2-chloro-phenyl)-vinyl]-quinolin-4-yl}-N*1*,N*1*-diethyl-pentane-1,4-diamine triphosphate 1g $378 2021-12-16 Buy

Properties

Melting point :223-225°
Boiling point :597.1±50.0 °C(Predicted)
Density :1.191±0.06 g/cm3(Predicted)
storage temp. :RT
solubility :Soluble in DMSO (up to 25 mg/ml with warming).
form :solid
pka :10.47±0.25(Predicted)
color :Light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

XIB4035 (10023-54-8) is a novel small molecule thought to be an agonist at the glial cell line-derived neurotrophic factor (GDNF) family receptor GFRα-1. It inhibits radiolabeled GDNF binding in Neuro-2A cells in a concentration dependent manner IC50?= 10.4 μM. Like GDNF, XIB4035 induced Ret autophosphorylation and promoted neurite outgrowth in Neuro-2A cells.1?Recent studies indicate that it enhances GFRα family receptor signaling in conjunction with ligand stimulation. Effective treatment for small-fiber neuropathy in mouse models of the disease.2,3? GDNF agonists may be a new class of Parkinson’s disease therapeutics.4

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