AS601245
|
- $50 - $2100
- Product name: AS601245
- CAS: 345987-15-7
- MF: C20H16N6S
- MW: 372.45
- EINECS:
- MDL Number:MFCD07772196
- Synonyms:AS601245;AS601245.TFA;JNK Inhibitor V;alpha-[2-[[2-(3-Pyridinyl)ethyl]amino]-4-pyrimidinyl]-2-benzothiazoleacetonitrile;2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile;2-Benzothiazoleacetonitrile, α-[2-[[2-(3-pyridinyl)ethyl]amino]-4-pyrimidinyl]-;CS-1619;2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile
33 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number5676CR
- Product description1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile
- Packaging25mg
- Price$810
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging5mg
- Price$169
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging10mg
- Price$286
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging25mg
- Price$485
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA163603
- Product description2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+%
- Packaging50mg
- Price$631
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0001543
- Product descriptionAS-601245 95.00%
- Packaging5MG
- Price$500.12
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging1mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging5mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging10mM(in 1mL DMSO)
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging10mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5942
- Product descriptionAS601245
- Packaging50mg
- Price$810
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611481
- Product descriptionAS601245
- Packaging50mg
- Price$984.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611481
- Product descriptionAS601245
- Packaging10mg
- Price$353.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611481
- Product descriptionAS601245
- Packaging5mg
- Price$268.6
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17542
- Product descriptionJNK Inhibitor V ≥98% (sum of isomers)
- Packaging1mg
- Price$56
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17542
- Product descriptionJNK Inhibitor V ≥98% (sum of isomers)
- Packaging5mg
- Price$149
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5676CR | 1,3-Benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile | 25mg | $810 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 5mg | $169 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 10mg | $286 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 25mg | $485 | 2021-12-16 | Buy |
| Ambeed | A163603 | 2-(Benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile 98+% | 50mg | $631 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0001543 | AS-601245 95.00% | 5MG | $500.12 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 1mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 5mg | $120 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 10mM(in 1mL DMSO) | $140 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 10mg | $210 | 2021-12-16 | Buy |
| ApexBio Technology | B5942 | AS601245 | 50mg | $810 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611481 | AS601245 | 50mg | $984.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611481 | AS601245 | 10mg | $353.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611481 | AS601245 | 5mg | $268.6 | 2021-12-16 | Buy |
| Cayman Chemical | 17542 | JNK Inhibitor V ≥98% (sum of isomers) | 1mg | $56 | 2024-03-01 | Buy |
| Cayman Chemical | 17542 | JNK Inhibitor V ≥98% (sum of isomers) | 5mg | $149 | 2024-03-01 | Buy |
Properties
Boiling point :635.6±65.0 °C(Predicted)
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL in DMSO
pka :5.32±0.10(Predicted)
form :White to yellow solid.
color :Light yellow to yellow
Density :1.366±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥14.25 mg/mL in DMSO
pka :5.32±0.10(Predicted)
form :White to yellow solid.
color :Light yellow to yellow
Safety Information
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Description
c-Jun N-terminal kinases (JNKs) phosphorylate c-Jun and regulate transcription in response to an array of inflammatory signals. JNK inhibitor V is an ATP-competitive inhibitor of JNK1, JNK2, and JNK3 (IC50s = 150, 220, and 70 nM, respectively). While initial studies demonstrated 10- to 100-fold selectivity for JNK isoforms over a panel of 25 other kinases, strong interactions of JNK inhibitor V with GSK3B, Pim-1, Pim-3, and other kinases, evaluated as a shift in thermal melting point, suggest additional targets exist. In vivo efficacy of JNK inhibitor V against JNK isoforms has been demonstrated in gerbils, mice, and rats via oral, intravenous, or intraperitoneal administration. This compound is commonly used to investigate the role of JNK signaling in cells and animals.Related product price
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$5-1390
Suppliers and manufacturers
career henan chemical co
![2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile](https://img.chemicalbook.com/ProductImageEN/2020-1/small/8bc99468-0952-462c-b2a2-9c76546d4ce8.jpg)
ATK CHEMICAL COMPANY LIMITED
InvivoChem
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
Sigma-Aldrich
Shanghai EFE Biological Technology Co., Ltd.
$9.80 /1KG
2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile CAS:345987-15-7
2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile CAS:345987-15-7
