ACK1-B19
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- $32 - $1056
- Product name: ACK1-B19
- CAS: 1234480-46-6
- MF: C24H27N7O2
- MW: 445.52
- EINECS:
- MDL Number:MFCD30742941
- Synonyms:ACK1-B19;XMD8-87;CS-2588;XMD-8-87;XMD8 87;XMD 8 87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-;XMD8-87 (ACK1-B19)
18 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Tocris
- TRC
Package
- 10
- 1mg
- 50
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 5 mg
- ManufacturerAK Scientific
- Product number6234DK
- Product description2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
- Packaging1mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560552
- Product descriptionXMD8-87 97%
- Packaging5mg
- Price$181
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560552
- Product descriptionXMD8-87 97%
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA560552
- Product descriptionXMD8-87 97%
- Packaging25mg
- Price$424
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2762
- Product descriptionXMD8-87 98%
- Packaging2x5mg
- Price$154
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2762
- Product descriptionXMD8-87 98%
- Packaging25mg
- Price$357.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23354
- Product descriptionXMD8-87 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23354
- Product descriptionXMD8-87 ≥98%
- Packaging5 mg
- Price$95
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23354
- Product descriptionXMD8-87 ≥98%
- Packaging10mg
- Price$191
- Updated2023-01-06
- Buy
- ManufacturerChemScene
- Product numberCS-6438
- Product descriptionXMD8-87 98.29%
- Packaging5mg
- Price$132
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6438
- Product descriptionXMD8-87 98.29%
- Packaging10mg
- Price$192
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6438
- Product descriptionXMD8-87 98.29%
- Packaging25mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6438
- Product descriptionXMD8-87 98.29%
- Packaging50mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6438
- Product descriptionXMD8-87 98.29%
- Packaging100mg
- Price$1056
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9940
- Product descriptionXMD8-87 >98%
- Packaging100mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number6061
- Product descriptionXMD8-87 ≥98%(HPLC)
- Packaging10
- Price$183
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6234DK | 2-[2-Methoxy-4-(4-methylpiperazin-1-yl)anilino]-11-methyl-5H-pyrimido[4,5-b][1,4]benzodiazepin-6-one | 1mg | $187 | 2021-12-16 | Buy |
| Ambeed | A560552 | XMD8-87 97% | 5mg | $181 | 2021-12-16 | Buy |
| Ambeed | A560552 | XMD8-87 97% | 10mg | $250 | 2021-12-16 | Buy |
| Ambeed | A560552 | XMD8-87 97% | 25mg | $424 | 2021-12-16 | Buy |
| Axon Medchem | Axon2762 | XMD8-87 98% | 2x5mg | $154 | 2021-12-16 | Buy |
| Axon Medchem | Axon2762 | XMD8-87 98% | 25mg | $357.5 | 2021-12-16 | Buy |
| Cayman Chemical | 23354 | XMD8-87 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23354 | XMD8-87 ≥98% | 5 mg | $95 | 2024-03-01 | Buy |
| Cayman Chemical | 23354 | XMD8-87 ≥98% | 10mg | $191 | 2023-01-06 | Buy |
| ChemScene | CS-6438 | XMD8-87 98.29% | 5mg | $132 | 2021-12-16 | Buy |
| ChemScene | CS-6438 | XMD8-87 98.29% | 10mg | $192 | 2021-12-16 | Buy |
| ChemScene | CS-6438 | XMD8-87 98.29% | 25mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-6438 | XMD8-87 98.29% | 50mg | $660 | 2021-12-16 | Buy |
| ChemScene | CS-6438 | XMD8-87 98.29% | 100mg | $1056 | 2021-12-16 | Buy |
| DC Chemicals | DC9940 | XMD8-87 >98% | 100mg | $550 | 2021-12-16 | Buy |
| Tocris | 6061 | XMD8-87 ≥98%(HPLC) | 10 | $183 | 2021-12-16 | Buy |
Properties
Density :1.283±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :10.18±0.20(Predicted)
color :White to yellow
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :10.18±0.20(Predicted)
color :White to yellow
Safety Information
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Description
XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC50s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC50 = >1 μM).Related product price
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