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ChemicalBook >> CAS DataBase List >> ABT-639

ABT-639

ABT-639 price.
  • $44 - $2520
  • Product name: ABT-639
  • CAS: 1235560-28-7
  • MF: C20H20ClF2N3O3S
  • MW: 455.91
  • EINECS:
  • MDL Number:MFCD29924737
  • Synonyms:ABT-639;4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]benzenesulfonamide;4-CHLORO-2-FLURO-N-(2-FLUOROPHENYL)-5-[(8AR)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YLCARBONYL]BENZENESULFONAMIDE;ABT-639, CID 46851313;(R)-4-chloro-2-fluoro-N-(2-fluorophenyl)-5-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)benzenesulfonamide;ABT-639 (ABT639;CS-2286;ABT-693
17 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number8455DG
  • Product descriptionAbt-639
  • Packaging5mg
  • Price$289
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28742
  • Product descriptionABT-639
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28742
  • Product descriptionABT-639
  • Packaging5mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28742
  • Product descriptionABT-639
  • Packaging10mg
  • Price$257
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28742
  • Product descriptionABT-639
  • Packaging25mg
  • Price$586
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5515
  • Product descriptionABT-639 99.36%
  • Packaging1mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5515
  • Product descriptionABT-639 99.36%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5515
  • Product descriptionABT-639 99.36%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5515
  • Product descriptionABT-639 99.36%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5515
  • Product descriptionABT-639 99.36%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004143
  • Product descriptionABT-639 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004143
  • Product descriptionABT-639 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004143
  • Product descriptionABT-639 98+%
  • Packaging50mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004143
  • Product descriptionABT-639 98+%
  • Packaging100mg
  • Price$1459
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9706
  • Product descriptionABT-639 >98%
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9706
  • Product descriptionABT-639 >98%
  • Packaging250mg
  • Price$1200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8455DG Abt-639 5mg $289 2021-12-16 Buy
Cayman Chemical 28742 ABT-639 1mg $44 2024-03-01 Buy
Cayman Chemical 28742 ABT-639 5mg $172 2024-03-01 Buy
Cayman Chemical 28742 ABT-639 10mg $257 2024-03-01 Buy
Cayman Chemical 28742 ABT-639 25mg $586 2024-03-01 Buy
ChemScene CS-5515 ABT-639 99.36% 1mg $180 2021-12-16 Buy
ChemScene CS-5515 ABT-639 99.36% 5mg $420 2021-12-16 Buy
ChemScene CS-5515 ABT-639 99.36% 10mg $600 2021-12-16 Buy
ChemScene CS-5515 ABT-639 99.36% 50mg $1800 2021-12-16 Buy
ChemScene CS-5515 ABT-639 99.36% 100mg $2520 2021-12-16 Buy
Crysdot CD31004143 ABT-639 98+% 5mg $243 2021-12-16 Buy
Crysdot CD31004143 ABT-639 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31004143 ABT-639 98+% 50mg $1042 2021-12-16 Buy
Crysdot CD31004143 ABT-639 98+% 100mg $1459 2021-12-16 Buy
DC Chemicals DC9706 ABT-639 >98% 100mg $650 2021-12-16 Buy
DC Chemicals DC9706 ABT-639 >98% 250mg $1200 2021-12-16 Buy

Properties

Boiling point :612.2±65.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:9.71(Max Conc. mg/mL);21.3(Max Conc. mM)
DMF:14.0(Max Conc. mg/mL);30.71(Max Conc. mM)
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.09(Max Conc. mM)
Ethanol:0.5(Max Conc. mg/mL);1.1(Max Conc. mM) form :A solid
pka :6.80±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ABT-639 is a T-type calcium channel blocker. It inhibits inactivated-state Cav3.2 channels with an IC50 value of 2.3 μM and inactivated-state Cav3.1 and Cav3.3 channels by 50 and 39%, respectively, when used at a concentration of 10 μM. ABT-639 selectively inhibits inactivated-state T-type calcium currents over resting-state currents in rat dorsal root ganglion (DRG) neurons (IC50s = 7.6 and >30 μM, respectively). It reverses the hind limb grip force deficit in a rat model of osteoarthritic pain induced by monoiodoacetic acid (MIA; ED50 = 2 mg/kg). ABT-639 also increases the paw withdrawal threshold in rat spinal nerve ligation (SNL) and chronic constriction injury (CCI) models of neuropathic pain in a dose-dependent manner and attenuates cold allodynia in the CCI rat model when administered at doses greater than or equal to 3 mg/kg.

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