ChemicalBook CAS DataBase List Cyromazine

Cyromazine synthesis

4synthesis methods

Product Name:Cyromazine
CAS Number:66215-27-8
Molecular formula:C6H10N6
Molecular Weight:166.18

Cyromazine is a triazine insect growth regulator used as an insecticide,it can be synthesized by the reaction of melamine and ammonia at room temperature and then cypromazine.

3397-62-4 Synthesis

3397-62-4
157 suppliers
$22.00/1g

765-30-0
486 suppliers
$10.00/25g

66215-27-8
472 suppliers
$30.00/5g

Yield:66215-27-8 96.37%

Reaction Conditions:

with sodium hydroxide at 70 - 85; pH=9.5; for 6 h;pH-value;Temperature;

Steps:

1.2; 2.2; 3.2; 4.2; 5.2; 6.2; 7.2; 1.2

(2) After the heat preservation is over, the temperature is lowered to below 70°C, 74.30g of cyclopropylamine is added, and then reheated to 85°C, and the temperature is kept and reacted for 6 hours. During the heating and holding period, 30wt% sodium hydroxide solution was used to adjust the pH to 9.5. After the reaction, the temperature was lowered to 30°C, filtered, and then beaten and washed with 400g water, then filtered, After drying, 173.69 g of cyromazine was obtained, the yield was 96.37%, and the purity by HPLC was 98.2%.

References:

CN112500360,2021,A Location in patent:Paragraph 0006; 0019-0028