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ChemicalBook >> CAS DataBase List >> (R)-2-((R)-6,7-diMethoxy-1-(4-(trifluoroMethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-Methyl-2-phenylacetaMide

(R)-2-((R)-6,7-diMethoxy-1-(4-(trifluoroMethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-Methyl-2-phenylacetaMide

(R)-2-((R)-6,7-diMethoxy-1-(4-(trifluoroMethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-Methyl-2-phenylacetaMide price.
  • $44 - $2500
  • Product name: (R)-2-((R)-6,7-diMethoxy-1-(4-(trifluoroMethyl)phenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-Methyl-2-phenylacetaMide
  • CAS: 913358-93-7
  • MF: C29H31F3N2O3
  • MW: 512.5632496
  • EINECS:
  • MDL Number:MFCD11110686
  • Synonyms:Almorexant HCI;(R)-2-((S)-1-(4-(trifluoromethyl)phenethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide hydrochloride;ACT078573 hydrochloride;AlMorexant (hydrochloride);(alphaR,1S)-3,4-Dihydro-6,7-dimethoxy-N-methyl-alpha-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide monohydrochloride;ACT-078573;ACT 078573;ACT078573;ACT-078573 HYDROCHLORIDE;ACT 078573 HYDROCHLORIDE;ACT078573 HYDROCHLORIDE;CS-942;Almorexant HCl (Act-078573)
22 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5750
  • Product descriptionAlmorexantHCl
  • Packaging100mg
  • Price$1812
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3241
  • Product descriptionAlmorexanthydrochloride
  • Packaging5mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3241
  • Product descriptionAlmorexanthydrochloride
  • Packaging10mg
  • Price$224
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3241
  • Product descriptionAlmorexanthydrochloride
  • Packaging50mg
  • Price$679
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA166116
  • Product descriptionAlmorexant hydrochloride
  • Packaging10mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBA166116
  • Product descriptionAlmorexant hydrochloride
  • Packaging50mg
  • Price$787.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13638
  • Product descriptionAlmorexant (hydrochloride) ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13638
  • Product descriptionAlmorexant (hydrochloride) ≥98%
  • Packaging5mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13638
  • Product descriptionAlmorexant (hydrochloride) ≥98%
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM146260
  • Product description(R)-2-((S)-6,7-dimethoxy-1-(4-methylphenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide 98%
  • Packaging100mg
  • Price$949
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2485
  • Product descriptionAlmorexanthydrochloride 99.88%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2485
  • Product descriptionAlmorexanthydrochloride 99.88%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2485
  • Product descriptionAlmorexanthydrochloride 99.88%
  • Packaging50mg
  • Price$828
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2485
  • Product descriptionAlmorexanthydrochloride 99.88%
  • Packaging100mg
  • Price$1440
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000291
  • Product descriptionAlmorexanthydrochloride 98+%
  • Packaging5mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000291
  • Product descriptionAlmorexanthydrochloride 98+%
  • Packaging10mg
  • Price$172
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5750 AlmorexantHCl 100mg $1812 2021-12-16 Buy
ApexBio Technology B3241 Almorexanthydrochloride 5mg $119 2021-12-16 Buy
ApexBio Technology B3241 Almorexanthydrochloride 10mg $224 2021-12-16 Buy
ApexBio Technology B3241 Almorexanthydrochloride 50mg $679 2021-12-16 Buy
Biosynth Carbosynth BA166116 Almorexant hydrochloride 10mg $225 2021-12-16 Buy
Biosynth Carbosynth BA166116 Almorexant hydrochloride 50mg $787.5 2021-12-16 Buy
Cayman Chemical 13638 Almorexant (hydrochloride) ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 13638 Almorexant (hydrochloride) ≥98% 5mg $193 2024-03-01 Buy
Cayman Chemical 13638 Almorexant (hydrochloride) ≥98% 10mg $341 2024-03-01 Buy
Chemenu CM146260 (R)-2-((S)-6,7-dimethoxy-1-(4-methylphenethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-N-methyl-2-phenylacetamide 98% 100mg $949 2021-12-16 Buy
ChemScene CS-2485 Almorexanthydrochloride 99.88% 5mg $144 2021-12-16 Buy
ChemScene CS-2485 Almorexanthydrochloride 99.88% 10mg $240 2021-12-16 Buy
ChemScene CS-2485 Almorexanthydrochloride 99.88% 50mg $828 2021-12-16 Buy
ChemScene CS-2485 Almorexanthydrochloride 99.88% 100mg $1440 2021-12-16 Buy
Crysdot CD31000291 Almorexanthydrochloride 98+% 5mg $102 2021-12-16 Buy
Crysdot CD31000291 Almorexanthydrochloride 98+% 10mg $172 2021-12-16 Buy

Properties

Melting point :196-200°C
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
color :White
Stability :Stable under recommended storage conditions., Stable Under Recommended Storage C

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Almorexant is a dual antagonist of the orexin 1 and 2 receptors (Kds = 1.3 and 0.17 nM, respectively). In a mouse model of narcolepsy, 100 mg/kg almorexant promoted nonrapid eye movement sleep and exacerbated cataplexy.

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