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ChemicalBook >> CAS DataBase List >> 2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine

2'-deoxy-2'-fluoro-2'-C-methylcytidine price.
  • $50 - $1600
  • Product name: 2'-deoxy-2'-fluoro-2'-C-methylcytidine
  • CAS: 817204-33-4
  • MF: C10H14FN3O4
  • MW: 259.23
  • EINECS:200-001-2
  • MDL Number:MFCD13176566
  • Synonyms:(2'R)-2'-deoxy-2'-fluoro-2'-methyl-Cytidine;PSI-6130;R 1656;PSI 6130;4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyr;2'-deoxy-2'-fluoro-2'-C-methylcytidine;R 1656;ethyl 4-broMo-1-Methyl-pyrrole-2-carboxylate;4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimi;4-AMino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidin-2(1H)-one
22 prices
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Brand
  • Ambeed
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging10mg
  • Price$361
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA669372
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+%
  • Packaging50mg
  • Price$1055
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146167
  • Product descriptionPSI6130 >99%
  • Packaging250mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146167
  • Product descriptionPSI6130 >99%
  • Packaging1g
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND28816
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • Packaging2mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND28816
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND28816
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND28816
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • Packaging25mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberND28816
  • Product description2'-Deoxy-2'-fluoro-2'-C-methylcytidine
  • Packaging50mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13575
  • Product descriptionPSI-6130
  • Packaging1mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13575
  • Product descriptionPSI-6130
  • Packaging5mg
  • Price$321
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM166468
  • Product description4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98%
  • Packaging10mg
  • Price$491
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0597
  • Product descriptionPSI-6130 99.39%
  • Packaging2mg
  • Price$180
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-0597
  • Product descriptionPSI-6130 99.39%
  • Packaging10mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000729
  • Product descriptionPSI-6130 98+%
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 5mg $228 2021-12-16 Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 10mg $361 2021-12-16 Buy
Ambeed A669372 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98+% 50mg $1055 2021-12-16 Buy
Biorbyt Ltd orb146167 PSI6130 >99% 250mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb146167 PSI6130 >99% 1g $765 2021-12-16 Buy
Biosynth Carbosynth ND28816 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 2mg $50 2021-12-16 Buy
Biosynth Carbosynth ND28816 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 5mg $100 2021-12-16 Buy
Biosynth Carbosynth ND28816 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 10mg $150 2021-12-16 Buy
Biosynth Carbosynth ND28816 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 25mg $300 2021-12-16 Buy
Biosynth Carbosynth ND28816 2'-Deoxy-2'-fluoro-2'-C-methylcytidine 50mg $450 2021-12-16 Buy
Cayman Chemical 13575 PSI-6130 1mg $93 2024-03-01 Buy
Cayman Chemical 13575 PSI-6130 5mg $321 2024-03-01 Buy
Chemenu CM166468 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one 98% 10mg $491 2021-12-16 Buy
ChemScene CS-0597 PSI-6130 99.39% 2mg $180 2021-12-16 Buy
ChemScene CS-0597 PSI-6130 99.39% 10mg $420 2021-12-16 Buy
Crysdot CD31000729 PSI-6130 98+% 5mg $300 2021-12-16 Buy

Properties

Melting point :216-218℃
Boiling point :482.4±55.0 °C(Predicted)
Density :1.67
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Methanol (Slightly), Water (Slightly)
pka :12.86±0.70(Predicted)
form :Solid
color :White to Light Brown
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PSI-6130 is a nucleoside inhibitor of the NS5B RNA polymerase of hepatitis C virus (HCV; Ki = 4.3 μM). It inhibits HCV genotype 1b (GT-1b) Con1 and GT-1a H77 viral replication in Huh7 replicon cells using a luciferase-based assay (EC50s = 0.51 and 0.30 μM, respectively). PSI-6130 also inhibits replication of HCV GT-1b and GT-1a replicons from clinical isolates, with EC50 values ranging from 0.60 to 1.41 μM, and 0.20 to 0.43 μM, respectively, in the same assay. It has little or no activity against West Nile Virus (WNV), Dengue type 2 virus (DV), human immunodeficiency virus (HIV), or hepatitis B virus (HBV; EC90s = 46.3, >100, >100, and >10 μM, respectively).