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ChemicalBook >> CAS DataBase List >> N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide

N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide

N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide price.
  • $28 - $5180
  • Product name: N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide
  • CAS: 702675-74-9
  • MF: C23H26IN7O2S
  • MW: 591.47
  • EINECS:200-256-5
  • MDL Number:MFCD12546134
  • Synonyms:N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide;BX 795;N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)aMino]propyl]aMino]-2-pyriMidinyl]aMino]phenyl]-1-pyrrolidin;BX795/BX-795;N-(3-(5-IODO-4-(3-(THIOPHENE-2-CARBOXAMIDO)PROPYLAMINO)PYRIMIDIN-2-YLAMINO)PHENYL)PYRROLIDINE-1-CARBOXAMIDE;N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide BX-795;BX-795 hydrochloride;N-[3-[[5-iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-Pyrrolidinecarboxamide hydrochloride
45 prices
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  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • 2mg
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  • 1unit
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  • 1g
  • 10mM(in 1mL DMSO)
  • 1000mg
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1026-M005
  • Product descriptionBX-795 ≥95%
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2292AH
  • Product descriptionN-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2292AH
  • Product descriptionN-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide
  • Packaging100mg
  • Price$712
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging5mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging25mg
  • Price$184
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging50mg
  • Price$284
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging100mg
  • Price$436
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging250mg
  • Price$654
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA700044
  • Product descriptionN-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+%
  • Packaging1g
  • Price$1633
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000290
  • Product descriptionBX 795 95.00%
  • Packaging5MG
  • Price$328.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8222
  • Product descriptionBX-795
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8222
  • Product descriptionBX-795
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8222
  • Product descriptionBX-795
  • Packaging10mM(in 1mL DMSO)
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8222
  • Product descriptionBX-795
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8222
  • Product descriptionBX-795
  • Packaging50mg
  • Price$380
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1026-M005 BX-795 ≥95% 5mg $108 2021-12-16 Buy
AK Scientific 2292AH N-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide 10mg $190 2021-12-16 Buy
AK Scientific 2292AH N-(3-(4-(2-(2-Formamidothiophen-3-yl)propanamido)-5-iodopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide 100mg $712 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 5mg $46 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 10mg $85 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 25mg $184 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 50mg $284 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 100mg $436 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 250mg $654 2021-12-16 Buy
Ambeed A700044 N-(3-((5-Iodo-4-((3-(thiophene-2-carboxamido)propyl)amino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide 99+% 1g $1633 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000290 BX 795 95.00% 5MG $328.9 2021-12-16 Buy
ApexBio Technology A8222 BX-795 1unit $28 2021-12-16 Buy
ApexBio Technology A8222 BX-795 5mg $60 2021-12-16 Buy
ApexBio Technology A8222 BX-795 10mM(in 1mL DMSO) $85 2021-12-16 Buy
ApexBio Technology A8222 BX-795 10mg $110 2021-12-16 Buy
ApexBio Technology A8222 BX-795 50mg $380 2021-12-16 Buy

Properties

Melting point :>163°C (dec.)
Density :1.644
storage temp. :2-8°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
pka :12.57±0.70(Predicted)
color :white to light brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :VAVXGGRQQJZYBL-UHFFFAOYSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

3-Phosphoinositide-dependent protein kinase 1 (PDK1) is a serine-threonine kinase that phosphorylates and activates a range of other kinases, including PKB, PKA, and certain isoforms of PKC. BX-795 is a potent, ATP-competitive inhibitor of PDK1 in vitro (IC50 = 11 nM) and in cells (IC50 = 300 nM). At comparable concentrations, BX-795 also inhibits ERK8, MAPK-interacting kinase 2, Aurora B, Aurora C, MAP/microtubule affinity-regulating kinases 1-4, TNF receptor associated factor-associated NF-κB activator-binding kinase 1, IκB kinase ε, and additional kinases.

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