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ChemicalBook >> CAS DataBase List >> 5-TRANS FLUPROSTENOL

5-TRANS FLUPROSTENOL

5-TRANS FLUPROSTENOL price.
  • $87 - $680
  • Product name: 5-TRANS FLUPROSTENOL
  • CAS: 57968-83-9
  • MF: C23H29F3O6
  • MW: 458.47
  • EINECS:
  • MDL Number:MFCD05863949
  • Synonyms:9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17-18,19,20-TETRANOR-PROSTA-5E,13E-DIEN-1-OIC ACID;WWSWYXNVCBLWNZ-BDFMIYKPSA-N;Travoprost Impurity 1(5- trans Fluprostenol);5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-, [1R-[1α(E),2β(1E,3R*),3α,5α]]- (9CI);5-TRANS FLUPROSTENOL
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1461AH
  • Product description5-TransFluprostenol
  • Packaging5mg
  • Price$525
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16776
  • Product description5-trans Fluprostenol ≥95%
  • Packaging1mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16776
  • Product description5-trans Fluprostenol ≥95%
  • Packaging5mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16776
  • Product description5-trans Fluprostenol ≥95%
  • Packaging10mg
  • Price$680
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1461AH 5-TransFluprostenol 5mg $525 2021-12-16 Buy
Cayman Chemical 16776 5-trans Fluprostenol ≥95% 1mg $87 2024-03-01 Buy
Cayman Chemical 16776 5-trans Fluprostenol ≥95% 5mg $384 2024-03-01 Buy
Cayman Chemical 16776 5-trans Fluprostenol ≥95% 10mg $680 2024-03-01 Buy

Properties

solubility :DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 15 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol. 5-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date.

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