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ChemicalBook >> CAS DataBase List >> N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine price.
  • $21 - $2918
  • Product name: N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • CAS: 477600-74-1
  • MF: C13H19N5
  • MW: 245.32
  • EINECS:
  • MDL Number:MFCD09878608
  • Synonyms:N-methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;N-Methyl-N-((3R,4R)-4-Methylpiperidin-3-yl)-7HMethylpiperidin-3-yl)-7Hpyrrolo[ 2,3-d]pyriMidin-4-aMine;(3R,4R)-N,4-diMethyl-N-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}piperidin-3-aMine;7H-Pyrrolo[2,3-d]pyriMidin-4-aMine, N-Methyl-N-[(3R,4R)-4-Methyl-3-piperidinyl]-;N-Methyl-N-((3R,4R)-4-Methyl-piperidin-3-yl)-N-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine;(3R,4R)-Methyl{(4-Methylpiperidin-3-yl)(7H-pyrrolo[2,3-d]pyriMidin-4-yl)}aMine;1H-Pyrrolo[2,3-d]pyriMidin-4-aMine,N-Methyl-N-[(3R,4R)-4-Methyl-3-piperidinyl]- (9CI);H-Pyrrolo[2,3-d]pyriMidin-4-aMine
14 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 10μg
  • 50ug
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 100g
  • ManufacturerAK Scientific
  • Product numberX6723
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • Packaging100mg
  • Price$311
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA480878
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging100mg
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA480878
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging250mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA480878
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging1g
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA480878
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging5g
  • Price$322
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb601754
  • Product descriptionTFG
  • Packaging10μg
  • Price$290.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb601755
  • Product descriptionTFG
  • Packaging10μg
  • Price$290.7
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM152317
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%+
  • Packaging100g
  • Price$2918
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11118993
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95+%
  • Packaging250mg
  • Price$312
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11118993
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95+%
  • Packaging1g
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number146918
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging1g
  • Price$345
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number146918
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%
  • Packaging5g
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM296155
  • Product descriptionN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • Packaging100mg
  • Price$365
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number134371
  • Product descriptionTFG
  • Packaging50ug
  • Price$539
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X6723 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 100mg $311 2021-12-16 Buy
Ambeed A480878 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 100mg $21 2021-12-16 Buy
Ambeed A480878 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 250mg $48 2021-12-16 Buy
Ambeed A480878 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 1g $94 2021-12-16 Buy
Ambeed A480878 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 5g $322 2021-12-16 Buy
Biorbyt Ltd orb601754 TFG 10μg $290.7 2021-12-16 Buy
Biorbyt Ltd orb601755 TFG 10μg $290.7 2021-12-16 Buy
Chemenu CM152317 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95%+ 100g $2918 2021-12-16 Buy
Crysdot CD11118993 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95+% 250mg $312 2021-12-16 Buy
Crysdot CD11118993 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95+% 1g $780 2021-12-16 Buy
Matrix Scientific 146918 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 1g $345 2021-12-16 Buy
Matrix Scientific 146918 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 95% 5g $685 2021-12-16 Buy
TRC M296155 N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 100mg $365 2021-12-16 Buy
Usbiological 134371 TFG 50ug $539 2021-12-16 Buy

Properties

Melting point :157 - 162°C
Density :1?+-.0.06 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly, Heated)
form :Solid
pka :13.36±0.50(Predicted)
color :White to Off-White
InChI :InChI=1S/C13H19N5/c1-9-3-5-14-7-11(9)18(2)13-10-4-6-15-12(10)16-8-17-13/h4,6,8-9,11,14H,3,5,7H2,1-2H3,(H,15,16,17)/t9-,11+/m1/s1
InChIKey :XRIARWQZLGCQDM-KOLCDFICSA-N
SMILES :C1=NC(N(C)[C@@H]2[C@H](C)CCNC2)=C2C=CNC2=N1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

N-Methyl-N-((3S,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, is an intermediate in the synthesis of (3S,4R)-Tofacitinib (T528010), an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.