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ChemicalBook >> CAS DataBase List >> (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide price.
  • $9 - $10000
  • Product name: (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide
  • CAS: 368421-58-3
  • MF: C13H14F2N4OS
  • MW: 312.34
  • EINECS:609-299-8
  • MDL Number:
  • Synonyms:(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide;NaMe:Isavuconazole interMediate 8;(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide hydrosulfate monohydrate;Isavuconazole intermediate 8;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide Hydrate Hydrosulfate;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMid;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutraMide;Isavuconazole intermediate 8 ? ?(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
13 prices
Selected condition：
Brand
  • Alichem
  • Ambeed
  • Ark Pharm
  • Chemenu
  • ChemScene
  • Crysdot
  • Labseeker
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 100g
  • 200g
  • ManufacturerAlichem
  • Product number368421583
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide
  • Packaging5g
  • Price$280.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA401662
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging100mg
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA401662
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging250mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA401662
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging1g
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000096376
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging100mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000096376
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging250mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000096376
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97%
  • Packaging1g
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM186290
  • Product description(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+%
  • Packaging100g
  • Price$815
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-M3468
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
  • Packaging1g
  • Price$61
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11134576
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+%
  • Packaging5g
  • Price$267
  • Updated2021-12-16
  • Buy
  • ManufacturerLabseeker
  • Product numberSC-95911
  • Product description1H-1,2,4-Triazole-1-butanethioamide,β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-,(αR,βR)- 95
  • Packaging200g
  • Price$10000
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number50894
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
  • Packaging1mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberD446345
  • Product description(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide
  • Packaging1mg
  • Price$150
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 368421583 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 5g $280.8 2021-12-16 Buy
Ambeed A401662 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 100mg $9 2021-12-16 Buy
Ambeed A401662 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 250mg $11 2021-12-16 Buy
Ambeed A401662 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 1g $28 2021-12-16 Buy
Ark Pharm P000096376 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 100mg $17 2021-12-16 Buy
Ark Pharm P000096376 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 250mg $25 2021-12-16 Buy
Ark Pharm P000096376 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 97% 1g $62 2021-12-16 Buy
Chemenu CM186290 (2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+% 100g $815 2021-12-16 Buy
ChemScene CS-M3468 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide 1g $61 2021-12-16 Buy
Crysdot CD11134576 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamide 95+% 5g $267 2021-12-16 Buy
Labseeker SC-95911 1H-1,2,4-Triazole-1-butanethioamide,β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-,(αR,βR)- 95 200g $10000 2021-12-16 Buy
Medical Isotopes, Inc. 50894 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide 1mg $650 2021-12-16 Buy
TRC D446345 (2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide 1mg $150 2021-12-16 Buy

Properties

Melting point :198-200oC
Boiling point :536.4±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :11.54±0.29(Predicted)
color :Off-White
CAS DataBase Reference :368421-58-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide is an intermediate in the synthesis of Isavuconazole (I777830), an triazole based antifungal agent for the treatment of invasive fungal infections.

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